carrier screening

car·ri·er screen·ing

indiscriminate examination of members of a population to detect heterozygotes for serious disorders and counsel about the risks of marriages with other carriers, and by prenatal diagnosis where a married couple are both carriers; often sacrifices specificity to sensitivity and is most effectively applied to populations known to be at high risk.

car·ri·er screen·ing

(kar'ē-ĕr skrēn'ing)
Indiscriminate examination of members of a population to detect heterozygotes for serious disorders and provide subsequent counsel about the risks of marriages to other carriers, and by prenatal diagnosis when both spouses in a married couple are both carriers.

carrier screening

, carrier identification
Performing genetic tests on a person to see if he or she may carry a recessive trait that might be expressed after mating with another carrier of the trait. It is used in high-risk families or populations to screen for illnesses such as cystic fibrosis, Gaucher's disease, and Tay-Sachs disease.
References in periodicals archive ?
14 January 2014 - US molecular diagnostics firm Good Start Genetics Inc said yesterday that health insurer Tufts Health Plan would start covering its GoodStart Select carrier screening assay.
According to the company, its MiSeqDx Cystic Fibrosis System consists of the MiSeqDx next-generation sequencing instrument, two assays (the MiSeqDx Cystic Fibrosis Diagnostic Assay and the MiSeqDx Cystic Fibrosis Carrier Screening Assay) and associated software.
Carrier screening of populations provides the frequency of specific CFTR alleles in healthy populations for comparison with that in CF patient populations.
Physicians seeing patients for preconception or prenatal counseling should now be advising them about cystic fibrosis carrier screening, according to the American College of Obstetricians and Gynecologists.
The test comprises all cystic fibrosis-causing variants recommended for carrier screening purposes by the American College of Medical Genetics and Genomics (ACMG) and the American College of Obstetricians and Gynecologists (ACOG).
Molecular testing company Trovagene Inc (NASDAQ:TROV) revealed on Tuesday that the clinical study of its proprietary, urine-based HPV carrier screening test is progressing well.
In persons of Ashkenazi Jewish background, DNA-based carrier screening is possible because 3 mutations account for ~95%-98% of obligate TSD carriers (12, 13).
While the American College of Obstetricians and Gynecologists is scrambling to make cystic fibrosis carrier screening a routine part of obstetric care, the physicians at Kaiser Permanente of Northern California have their program firmly in place.
CHICAGO -- The American College of Obstetricians and Gynecologists is preparing to announce recommendations that are expected to widen the scope of who should be offered carrier screening for cystic fibrosis, Dr.
18 October 2013 - US molecular diagnostics firm Good Start Genetics Inc unveiled Thursday data showing that 8.4% of the carriers of genetic diseases identified by its Select carrier screening test would have been missed by other available technologies.
Our laboratory is the major testing site for CF carrier screening for the US Army healthcare system, and we needed to choose a method suitable for performing ~350 tests per week.
In a typical screening scenario, an obstetrician will introduce the option of carrier screening for CF, usually by giving the patient a brochure on the subject that's published by ACOG, having the patient watch a video that the physician has prepared, or discussing the option with the patient.

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