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We made a 4-inch-deep one that holds 16 to 18 gallons of the carrageenin solution; its rectangular frame is made of two 72-inchlong 2-by-4s and two 45-inch-long 2-by-4s nailed to a 48- by 72-inch sheet of 3/8-inch plywood.
Before adding carrageenin bath, you might want to fill the tub with water to be sure it doesn't leak.
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat.
Carrageenin, dextran, formalin, histamine, diphenhydramine, capsaicin, and dexamethasone were obtained from Sigma Chem.
25 ml 1% carrageenin in saline, into the right pleural cavity.
after 3 hrs of drug treatment in carrageenin induced paw edema (Table 1) whereas the standard drug produced 61.
Since it is evident that carrageenin induced oedema is commonly used as an experimental animal model for acute inflammation and is believed to be biphasic, of which the first phase is mediated by the release of histamine and 5-HT in the early stage followed by kinin release and then prostaglandin in the later phase (Castro et al.