[1,2,3,4] Hypoparathyroidism leading to decreased serum calcium, clinically may present with muscle cramps, perioral and peripheral paraesthesia, carpopedal
spasm or tetany, and/or confusion.
 The main clinical features of the disease are hypocalcemic symptoms such as perioral numbness, paresthesia, and carpopedal
The diagnosis of vitamin D deficiency is based on a combination of clinical features (which may include bone pain and tenderness, carpopedal
spasms, diffuse limb pains, deformities of the lower limbs and generalized weakness, fractures, etc.), laboratory results, and radiologic findings.
Trousseau's sign is positively noted by inflating a blood pressure cuff above systolic pressure for up to three minutes and looking for a carpopedal
Sex, hypocalcemia in ss-thalassemia major, symptomatic hypocalcemia, presence of paresthesias and numbness, myalgias, hyperpigmentation and carpopedal
spasm were variables.
23-year-old female presented to the Emergency Room with carpopedal
spasms and tingling numbness in hands.
Physical examination revealed carpopedal
spasm and overactive tendon reflexes.
Tetany as a result of muscular spasm and carpopedal
spasm were positive at the time of admission while Chvostek's and Trousseau's signs were negative although she had no dysmorphic features.
The common clinical manifestations of hypoparathyroidism include tingling and numbness, carpopedal
spasm, seizures, and neurocognitive dysfunction (3).
Also, patients with prolonged hypocalcemia had a significantly higher incidence of serious sequelae, including carpopedal
spasms and signs of tetany.