carnosine


Also found in: Encyclopedia, Wikipedia.

carnosine

 [kahr´no-sēn]
a dipeptide composed of beta-alanine and histidine, found in skeletal muscle of vertebrates.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

car·no·sine

(kar'nō-sēn),
N-β-alanyl-l-histidine; the dominant nonprotein nitrogenous component of brain tissue, first found in relatively high amounts in muscle; chelates copper and activates myosin ATPase.
Synonym(s): ignotine, inhibitine
[L. carnosus, fleshy, fr. caro, flesh, + -ia]
Farlex Partner Medical Dictionary © Farlex 2012

carnosine

A dipeptide composed of beta-alanine and histidine that is concentrated in skeletal muscle and the brain. While its function is unknown, carnosine has antioxidant properties, counteracts glycation, chelates divalent metal ions and acts as a buffer, stabilising the pH of anaerobically contracting muscle.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes.
Grossman advises supplementation of N-acetyl carnosine, bilberry, resveratrol, melatonin, and milk thistle in cataract treatment.
Indeed, the researchers noted substantial increases in certain antioxidants, including ergothioneine and carnosine.
Indeed, the researchers noted substantial increases in certain antioxidants, including ergothioneine and carnosine.In an earlier study, the same team of researchers showed that, as we age, the number of metabolites decline.
On the other hand, it is important to highlight that for the CNP is an enzyme that has been previously reported under different denominations (glycine-glycine dipeptidase, carnosine dipeptidase) agreeing to the MEROPS peptidase database (http://merops.sanger.ac.uk/index.
These products usually contain n-acetyl carnosine as the active ingredient.
(16) pioneered supplementation with BA, a non-essential amino acid, to endogenously synthesize muscle carnosine. Carnosine acts as a hydrogen ion buffer in active muscle, attenuating the decrease in muscle pH due to hydrogen ion accumulation with strenuous movement, thereby reducing fatigue (7).
According to the company, the new allowed claims are directed to methods of delaying muscle fatigue through supplementation with instant release beta-alanine in times and amounts to increase muscle carnosine levels beyond that obtainable through diet alone.
The following water-soluble compounds - lithium ascorbate, carnosine, and ascorbic acid as a standard antioxidant were used for comparative study of blood compounds protection against ethanol.
The reduced quadratic mixture model predicted that glycerol, fenoldopam mesylate, carnosine, and DMSO added as single additives significantly affected the number of live cells (Table 4).