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Six analogues of fentanyl, including carfentanil, are being considered.
Hogan told lawmakers during a nearly two-hour hearing before the Senate Health, Labor and Pensions Committee that more is needed in the way of federal funding and efforts to stop powerful synthetic opioids such as fentanyl and carfentanil from entering the country from Mexico and China.
Unfortunately, the trend is toward more powerful versions of opioids, transitioning from opioids that were legally prescribed, to heroin and now to illicit fentanyl and carfentanil.
But the study found that the projections may actually be low, especially with the rapid rise of heroin, fentanyl and carfentanil use.
The report found that out of a total of 5,152 opioid overdose deaths, almost 3,000 tested positive for fentanyl, and more than 700 tested positive for drugs that have similar chemical structures to fentanyl (fentanyl analogs)--including the extremely potent fentanyl analog carfentanil, which is used to sedate large animals.
fentanyl analogues [such as carfentanil, furanylfentanyl, and acetylfentanyl] are increasingly contributing to a complex illicit opioid market with significant public health implications," investigators said in a report from the Centers for Disease Control and Prevention (MMWR.
In addition, fentanyl analogs such as acetylfentanyl, furanylfentanyl, and carfentanil are being detected increasingly in overdose deaths (5,6) and the illicit opioid drug supply (7).
The program will also need to determine the best ways to continue to make kits available, and how to respond to new challenges arising from the use of analogues of fentanyl, such as carfentanil.
But by tweaking just a couple compounds, fentanyl can turn into carfentanil, acrylfentanyl and other analogs that can cause an individual to overdose just by touch.
Tambien Canada ha sufrido un elevado numero de sobredosis por el fentanil y el carfentanil, opiaceos de alta potencia utilizados para adulterar la droga vendida en las calles.
Variations of fentanyl such as carfentanil are 10,000 times more potent than morphine and can cause respiratory arrest in those who breathe trace particles of the narcotic.
The Houston Forensic Science Center also identified another potent synthetic opioid, carfentanil, in a drug evidence sample earlier this year.