cardiotoxin

car·di·o·tox·in

(kar'dē-ō-tok'sin),
1. A poisonous glycoside with specific cardiac effects. For example, causes irreversible depolarization of cell membranes.
2. Specifically, one of the toxic principles from cobra venom.
3. Any substance that can cause heart damage with toxic doses.
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References in periodicals archive ?
Cardiotoxin was isolated from Naja naja atra (Chinese cobra) venom; this toxin was able to potentiate platelet aggregation induced by ADP, thrombin, collagen, and venom phospholipase [A.sub.2] [41].
2012 out of the EBs, the [10.sup.5] cells) were [53] clusters [Pax3.sup.+] transplanted into the and muscle of immunodeficient [Pax7.sup.+] NOG (NOD-Shiscid-IL- cells were 2R[gamma]null) mice randomly distributed at following cardiotoxin day 21.
Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin Ill-treated A549 cells.
Mice were randomly divided into two groups: (1) cardiotoxin (CTX)-injected (CX, n = 15) and (2) CTX-injected with MENS treatment (MX, n = 15) groups.
Effects of a cardiotoxin from Naja naja kaouthia venom on skeletal muscle: involvement of calcium-induced calcium release sodium ion currents and phospholipases A2 and C.
Haemolysis: Studies have demonstrated that the venom from cobra has significant hemolytic activity, including a synergistic effect of the cardiotoxin with phospholipidase A2.
Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells.
NNAV contains cobra venom factor (CVF), cardiotoxin (CTX), cobratoxin (or cobrotoxin), phospholipases A2 (PLA2), and many other components.
Key Words: Magnesium sulphate, Wheat pill, Aluminum phosphide, Phosphine, Cardiotoxin
Most studies of skeletal muscle regeneration use acute models of injury and repair, such as sterile destruction of myofibers by either injection of toxins, such as cardiotoxin, notexin, or barium chloride, or by performing freeze crush injuries.

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