cardiotoxic

cardiotoxic

 [kahr´de-o-tok″sik]
having a poisonous or deleterious effect upon the heart.

car·di·o·tox·ic

(kar'dē-ō-tok'sik),
Having a deleterious effect on the action of the heart, due to poisoning of the cardiac muscle or of its conducting system.
[cardio- + G. toxikon, poison]

car·di·o·tox·ic

(kahr'dē-ō-tok'sik)
Having a deleterious effect on the action of the heart, due to poisoning of the cardiac muscle or of its conducting system.
[cardio- + G. toxikon, poison]

cardiotoxic

Having a damaging or poisoning effect on the heart.

car·di·o·tox·ic

(kahr'dē-ō-tok'sik)
Denotes with deleterious effect on action of heart, due to poisoning of the cardiac muscle or of its conducting system.
[cardio- + G. toxikon, poison]
References in periodicals archive ?
Hence, studies were conducted on the mechanism of the cardiotoxic side effects of local anaesthetics and research for drugs with less cardiotoxic profile is continuing.
First-line treatments are sertraline and citalopram; among contraindicated treatments are tricyclic antidepressants and monamine oxidase inhibitors, which have cardiotoxic side effects, the advisory states.
Radiation and anthracyclines are directly cardiotoxic, while the VEGF inhibitors appear to frequently cause hypertension.
The guidelines recommend cardiac tests for patients undergoing chemotherapy with known cardiotoxic agents, discuss the cardiac problems linked to radiation treatment, and suggest which cardiac tests are useful for patients who underwent previous radiation to the chest and now need chemotherapy.
The cardiotoxic interaction between trastuzumab and anthracycline also came to the fore in terms of an increased incidence of severe chronic heart failure, as noted in other studies.
The persistence of increased concentrations for more than 72 h suggests that in these patients the increase in NT-proBNP reflects the presence of an underlying reduced functional myocardial reserve or reduced cardiac tolerance to cardiotoxic agents.
"In contrast with cocaine, long-term methamphetamine use seems to have a direct, cardiotoxic effect, and promotes the development of severe, nonischemic, dilated cardiomyopathy," according to Dr.
Women who do use cocaine, however, are much more likely than men to experience cardiotoxic effects.
For nearly three decades, reports have appeared that describe the fatal cardiotoxic effects of this drug (6-8).
The levorotatory isomers were shown to have a safer pharmacological profile with less cardiotoxic and neurotoxic effects and it is attributed to its faster protein binding rate.
But they worried about possible cardiotoxic effects of exogenous testosterone in a vulnerable HF population.

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