Under emerging medical guidelines, physicians now look at treating cardiorenal syndrome
, a condition in which acute or chronic dysfunction of either the heart or the kidney can induce dysfunction of the other," he told Gulf News.
The year-long campaign, Destination Healthy Heart: A Road Map to Managing Heart Failure will kick-off February 8 and will consist of a roll out of a series of topics focusing on different conditions related to heart failure such as: Cardiorenal Syndrome
, Atrial Fibrillation, Viral Illness, Cardiotoxins, Takotsubo (Broken Heart Syndrome), and more.
Cardiologists mainly from Athens, Greece, address the role of biomarkers like C-reactive protein, interleukins, fibrinogen, peptides, adhesion molecules, microRNAs, and proinflammatory cytokines in early atherosclerosis, hypertension, hyperlipidemia, acute coronary syndromes, congestive heart failure, pulmonary embolism, coronary artery bypass grafting, peripheral vascular disease, cardiorenal syndrome
, coronary artery disease, heart failure, cardiac arrhythmias, and antiplatelet treatment, as well as the role of genetics and genomics.
We hypothesize that increased BNP and NT-proBNP plasma concentrations reflect the homeostatic response of the heart to disturbed renal function in the context of a cardiorenal syndrome
, which is suggested to amplify progression of both CHF and CKD (12).
7 Fluid overload and cardiorenal syndrome
in heart failure: two sides of the same coin?
Written by cardiologists and other physicians from the US and Europe, each chapter is organized around a question, which relates to the use of digoxin, cell therapy, pulmonary hypertension, pharmacogenics and pharmacogenetics, anticoagulation, oral and intravenous vasodilators, fluid overload and cardiorenal syndrome
, endomyocardial biopsy, exercise training, the effects of metabolic syndrome, obesity, revascularization in asymptomatic patients, blood based biomarkers, atrial fibrillation, nutraceuticals, and statins.
Trials for heart failure, cardiorenal syndrome
, and chronic kidney disease are also anticipated.
In the 29 papers, faculty from the course address the different varieties and subtypes of the cardiorenal syndrome
, their epidemiology, management, and prevention; multiple organ dysfunction syndromes; fluid assessment and management in the critically ill; critical care issues; the results of the most recent Acute Dialysis Quality Initiative Consensus Conference; new diagnostic approaches based on early biomarkers of acute kidney injury; advances in technology for renal replacement therapy and multiple organ support therapy; the potential role of extracorporeal therapies in patients affected by H1N1 influenza; and the most recent trials.
The approach may have applications in numerous clinical situations including prevention of contrast-induced nephropathy, acute ischemic renal failure in high-risk surgical settings, and cardiorenal syndrome
in acute heart failure.
Study to Evaluate Aquapheresis Versus Standard Drug Therapy in Patients Hospitalized with Both Acute Decompensated Heart Failure and CardioRenal Syndrome
These causes include contrast-induced nephropathy (CIN), cardiorenal syndrome
and other forms of acute kidney injury (AKI).
Physicians are assessing these systems in patients at risk for two major conditions that can cause kidney dysfunction: Radiocontrast nephropathy (RCN), one of the most common causes of acute kidney failure among hospitalized patients; and cardiorenal syndrome
(CS), kidney dysfunction that occurs in a large number of patients hospitalized with heart failure.