* Resting the heart while perfusing the kidneys, Aortix aims to treat heart failure symptoms by disrupting the cardiorenal syndrome
Heart failure with preserved ejection fraction (HFpEF) constitutes the main feature of uremic cardiopathy and is often referred to as type 4 cardiorenal syndrome
Patients with suppressed cardiac function, decreased cardiac output and cardiac index had higher probability of developing HRS type 1 within 3 months supporting the association between cardiac dysfunction and renal failure in cirrhosis, the so-called "cardiorenal syndrome
For example, in patients with cardiorenal syndrome
, negative fluid balance should be established as early as possible, and dehydration can be slowed once lung edema is reduced.
To decrease inconsistency and confusion, the Acute Dialysis Quality Initiative (ADQI) defines cardiorenal syndrome
as disorders of the heart and kidneys, whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other.
It is well established that heart performance and kidney function are closely interconnected and dysfunction of one organ often leads to a deterioration of the function of another which is known as cardiorenal syndrome
in acute decompensated heart failure.
Results from this study showed the usefulness to include plasma NGAL measurement besides other routinely biomarkers, such as creatinine, in patients with cardiorenal syndrome
to early identify AKI development.
Acute decompensated heart failure and the cardiorenal syndrome
. Crit Care Med.
Dialysis-induced myocardial stunning: the other side of the cardiorenal syndrome
. Rev Cardiovasc Med.
"Under emerging medical guidelines, physicians now look at treating cardiorenal syndrome
, a condition in which acute or chronic dysfunction of either the heart or the kidney can induce dysfunction of the other," he told Gulf News.
: Cardiorenal syndrome
involves altering cardiac and renal function.