Cardioprotective Natural Products: Promises and Hopes
Amarin intends to submit an sNDA to the FDA in early 2019 seeking approval to expand the label for Vascepa based on the
cardioprotective effect of Vascepa demonstrated in the REDUCE-IT study.
With around half of individuals withType 1 diabetesdiagnosed before the age of 14, the authors of the study said it highlights a need to consider wider and earlier use of
cardioprotective measures such as statins and blood pressure lowering drugs for those affected.
7, 2018 (HealthDay News) -- Elevated high-density lipoprotein cholesterol (HDL-C) may not always be
cardioprotective in postmenopausal women, according to a study published online July 19 in Arteriosclerosis, Thrombosis, and Vascular Biology.
"HIV infection is independently associated with a higher risk for developing heart failure, and this excess risk does not appear mediated through atherosclerotic disease pathways or differential use of
cardioprotective medications," Alan S.
This hormone has been shown to have a beneficial or
cardioprotective effect on the inner layer of artery wall called endothelium.
"Our findings show that Alendronate is potentially
cardioprotective in hip fracture patients," said Ching-Lung Cheung, from the University of Hong Kong.
Although the sigma-1 receptor agonist PRE-084 exhibits a
cardioprotective effect in some studies, the benefits in cases of myocardial ischemia/reperfusion (I/R) are not clear.
The
cardioprotective potential of Coriandrum sativum against salbutamol induced cardiac injury in another experimental model also favored the increased in cardiac markers after administration of two doses of salbutamol (Kousar et al., 2012).
A Mediterranean diet rich in virgin olive oil (VOO) could enhance the
cardioprotective benefits of HDL ("good") cholesterol, say researchers writing in Circulation, Feb.
In addition, most high-potassium foods also contain other
cardioprotective nutrients.
Besides cardiodepressive effects, sevoflurane also exerts
cardioprotective effects as shown by reduced myocardial ischemic injury in rats [10,11].
