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Because the phenolic hydroxyl in polydatin is similar to the chemical structure of vitamin E (a common anti-oxidant in our body), we hypothesized that the free radical-eliminating effect of polydatin might be another potential mechanism mediating cardioprotection.
Cardioprotective effect of polydatin against ischemia/reperfusion injury: Roles of protein kinase C and mito [K.sub.ATP] activation
Seven day oral supplementation with Cardax (disodium disuccinate astaxanthin) provides significant cardioprotection and reduces oxidative stress in rats.
Beyond eye health: how astaxanthin combats degenerative disease
One of the main points of the review included that resveratrol exhibits therapeutic potential for cancer chemoprevention as well as cardioprotection.
Why red wine is the elixir of health
In the Medical Research Council (MRC) trial, the benefits of the diuretic were diluted whenever a [beta]-blocker was added and vanished completely with 13-blocker monotherapy The more [beta]-blocker they took, the less cardioprotection they had.
Should [beta]-blockers remain first-line therapy for uncomplicated hypertension in the elderly? (Pro & Con)
The role of hormone replacement in cardioprotection may become more dearly defined in a few years when the Women's Health Initiative and the HERS II continuation study are published.
Estrogen Shouldn't Replace Exercise
10-12 From its large proprietary library of prolyl hydroxylase inhibitors, FibroGen is developing clinical and preclinical candidates designed to selectively activate HIF biology for the treatment of anemia and elicit a rapid, multifactorial, cytoprotective response for treating or preventing conditions resulting from acute ischemic injury and/or inflammation, including cardioprotection and inflammatory bowel disease.
FibroGen Reports Dose-finding Data from Phase 2b Study of FG-4592 for Anemia Correction and Maintenance in Chronic Kidney Disease Patients
Autophagy leads to cardioprotection by removing misfolded protein or dysfunctional mitochondria or maintaining energy homeostasis [41].
Role of TFEB Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice
The cardioprotection afforded by DG pretreatment was paralleled by enhancements in mitochondrial antioxidant status and membrane structural integrity, as well as a decrease in the sensitivity of mitochondria to [Ca.
Acute treatment with Danshen-Gegen decoction protects the myocardium against ischemia/reperfusion injury via the redox-sensitive PKC[epsilon]/m[K.sub.ATP] pathway in rats
Cardioprotection in humans by carotenoids has been inferred from observational and epidemiologic studies, however, direct studies of cardioprotection and myocardial salvage by carotenoids are lacking.
Astaxanthin
The effects of the omega-3 fatty acids in fish oil include direct anti-inflammatory activity in joints and possible long-term cardioprotection.
Fish oil for rheumatoid arthritis
The findings suggest that "none of these drugs should be used for cardioprotection," they said (Lancet 359[9301]:118-23, 2002).
NSAIDs questioned. (Clinical Capsules)
The role of drug delivery in various cardiovascular disorders such as myocardial ischemia, hypertension and hypercholesterolemia is discussed, as is cardioprotection.
Research and Markets: Updated Cardiovascular Drug Delivery Study - Examining Technological Innovation, Key Players and Markets (2010 to 2020)
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