cardiomyocyte


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cardiomyocyte

(kar″dē-ō-mī′ŏ-sīt″) [ cardio- + myocyte]
A cardiac muscle cell. The cell is striated, containing thick and thin proteins arranged linearly. These filaments are composed, like other striated muscle cells, largely of actin and myosin. The cell has an abundant supply of mitochondria that supply the energy needed by the cell for regular muscular contraction.

cardiomyocyte

A heart muscle cell.
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The researchers also found that early cardiomyocytes exposed to pIC before implantation in mouse hearts matured faster than those not primed with the compound.
By assessing the six OGD-NR in vitro models commonly used in previous works, we found that the cardiomyocyte injury did not meet the characteristics of MIRI in vivo , neither further injury caused by SIR treatment nor pathophysiological characteristics produced by SIR treatment.
For comparisons of gene expression to human tissue-specific gene expression from GTEx (GTEx Consortium, 2015), normalized counts for each cardiomyocyte donor were combined with median tissue counts downloaded from the GTEx portal and overlapping genes were kept (n = 2640).
Cardiomyocytes, the principal cell type found in the heart orchestrates the cardiac contractions and ensures efficient blood flow throughout the body.
Multiplex immunostaining and patch clamp analysis have also revealed the presence of all three cardiomyocyte types (atrial, ventricular, and pacemaker) in iCMs, therefore increasing the risk of arrhythmias [16].
have summarized that altered expression levels of MST1 could not affect the size of cardiomyocytes but an upregulated MST1 level increased cardiomyocyte apoptosis [18].
Assessment of cardiomyocyte DNA synthesis in normal and injured adult mouse hearts.
In myocardium from CLP-induced septic shock rats, cardiac BDNF level was significantly reduced accompanied with increased cardiomyocyte apoptosis and enhanced oxidative stress, which were associated with cardiac dysfunction and increased mortality rate.
Therefore, in the current study, we tested oleuropein with neonatal rat cardiomyocytes cells subjected to SI/R in vitro to investigate its cardioprotective effect and further explore the possible underlying mechanisms related to antiapoptotic property.
Several miRNAs serve as protective factor of cardiomyocyte survival by suppressing/inhibiting the expression of proapoptotic molecules.
Besides, patient-specific iPSC-derived cardiomyocyte application for in vitro reproduction of CVD pathologic phenotype, studying CVD molecular mechanisms, and search for new therapy methods is considered.