NKx2.5 is positively regulated by HMGA2 through Smad1/4 of the TGF-[beta] pathway and it is a crucial factor for cardiogenesis
Schmitt et al., "A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis
and disease," Cell, vol.
recently hypothesized that hypertrabeculation is not a failure of myocardial compaction, but rather an aberration of mammalian cardiogenesis
Li et al., "Dysregulation of cardiogenesis
, cardiac conduction, and cell cycle in mice lacking miRNA1-2," Cell, vol.
Schoenwolf, "Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis
," Gene, vol.
In the early phase of cardiogenesis
, cardiomyocytes are in an active proliferative state, thus requiring an enhanced metabolic support to increase their biomass and to allow cell division.
We used the period spanning 2-8 weeks post-conception as the exposure window, based on evidence that cardiogenesis
is completed during this time (Moorman et al.
Proinsulin stimulates cardiogenesis
and prevents apoptosis during neurulation (11).
Embryonic heart progenitors and cardiogenesis
. Cold Spring Harb.
Prior to Endologix, Fauls held management positions of increasing responsibility in regulatory and clinical affairs positions at major global medical technology companies including Edwards Life Sciences, Cardiogenesis
Las cadherinas E y N son las prototipicas en los tejidos epiteliales y mesenquimales, respectivamente, y estan involucradas en la regulacion de eventos morfologicos como gastrulacion, neurulacion, cardiogenesis
y somitogenesis .