The patients with refusal, emergency surgery, allergy to trial drugs, history of drug and alcohol abuse, patients on cardioactive
drugs like alpha 2 agonist, methyldopa, beta blockers, calcium channel blocker, ACE inhibitors, anticipated difficult intubation (Mallampati grade III or IV), pregnancy and patients with severe systematic disorders like diabetic, musculoskeletal and neurological disease were excluded from the study.
Those with present or history of any acute or chronic disease state and history of taking cardioactive
drugs such as antihypertensive and antilipidemics were excluded from the study.
Students having history of hypertension, any cardiac or renal disorders, smokers, those taking any cardioactive
drug, or attending a recent weight loss program were excluded from the study.
Value of BNP to estimate cardiac risk in patients on cardioactive
treatment in primary care.
Our screening approach included media- and vehicle controls as well as treatments at four concentrations with three drugs of known cardioactive
mechanisms: the [beta]-adrenergic receptor agonist isoproterenol (ISO, positive inotrope), the [beta]-adrenergic receptor antagonist propranolol (PRO, negative inotrope), and the hERG channel inhibitor cisapride (CIS, QT prolongation).
Kaichi et al., "The effects of cardioactive
drugs on cardiomyocytes derived from human induced pluripotent stem cells," Biochemical and Biophysical Research Communications, vol.
In conclusion, LC described effects could be useful in association with other cardioactive
The first applications of the bioreactor will be to evaluate the efficacy and toxicity of cardioactive
drugs on human ventricular cardiac organoid chambers (hvCOC), a part of Novoheart's MyHeart Platform.
Dobutamine: a new synthetic cardioactive
The plant contains cardioactive
glycosides and flavanoid glycosides, which means that it increases the force of the heart, regulates the beat for distension of the ventricles, increases size and strength of the pulse, slows down a rapid feeble pulse, eliminates fluid retained in the tissue (oedema) and acts as a cardio and gastric tonic.
Chemical constituents: Carissone, carindone, carinol and four crystalline substances, viz: A, B, a cardioactive
and B-Sitosterol, Caffeic acid, odoroside B,C,G and H and evomonoside (Prajapati et al., 2003; Khare, 2007).