cardinal

car·di·nal

(kar'di-năl),

Chief or principal; in embryology, relating to the main venous drainage.

[L. cardinalis, principal]

cardinal

/car·di·nal/ (kahr´dĭ-n'l)

1. of primary or preeminent importance.

2. in embryology, pertaining to the main venous drainage.

cardinal

[kär′dənal]

Etymology: L, cardo, hinge

pertaining to something so fundamental that other things hinge on it, such as a cardinal trait that influences one's total behavior.

CARD8

A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.