carcinoma ex pleomorphic adenoma

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Related to carcinoma ex pleomorphic adenoma: hemangiopericytoma, Warthin tumor

car·ci·no·ma ex ple·o·mor·phic ad·e·no·ma

(kar'si-nō'mă eks plē-ō-mōr'fik ad'ĕ-nō'mă),
Carcinoma arising in a benign mixed tumor of a salivary gland, characterized by rapid enlargement and pain.
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References in periodicals archive ?
In a recent report, Persson and colleagues (14) have postulated that 12q genes (in particular MDM2) may be a main target gene for malignant transformation in carcinoma ex pleomorphic adenoma. In addition, HMGA2 has been shown to be the target gene in pleomorphic adenoma with translocations involving 12q14-15 and is frequently coamplified with MDM2.
One case of carcinoma ex pleomorphic adenoma was seen in our study.
In our case of Carcinoma ex pleomorphic adenoma the tumor showed irregular grey brown infiltrating areas, with areas of necrosis & hemorrhage.
Carcinoma ex pleomorphic adenoma. Barnes EL, Eveson JW, Reichart P, Sidransky D, eds.
Carcinoma ex pleomorphic adenoma: pathologic analysis of 73 cases.
Intracapsular carcinoma ex pleomorphic adenoma: report of a case with unusual metastatic behaviour.
Carcinoma ex pleomorphic adenoma, an epithelial malignancy arising in or associated with a mixed tumor, can demonstrate a variety of histologic subtypes.
However, if left untreated, up to 5 percent may become malignant (Carcinoma ex pleomorphic adenomas).