carcinogenesis


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Related to carcinogenesis: chemical carcinogenesis

carcinogenesis

 [kahr″sĭ-no-jen´ĕ-sis]
production of cancer.
Multistep model of carcinogenesis. The stepwise genetic alterations that lead to colorectal cancer. From Aspinall and Taylor-Robinson, 2001.

car·ci·no·gen·e·sis

(kar'si-nō-jen'ĕ-sis),
The origin or production, or development of cancer, including carcinomas and other malignant neoplasms.
[carcino- + G. genesis, generation]

carcinogenesis

[kär′sinəjen′əsis]
the process of initiating and promoting cancer. Compare malignant transformation, oncogenesis, sarcomagenesis, tumorigenesis.

carcinogenesis

Transformation, tumourigenesis Oncology A series of genotypic and phenotypic changes that result in a cell being identified as malignant by virtue of its metastatic potential. See Cancerization, Chemical carcinogenesis, Inducer, One-hit/two-hit model, Proto-oncogenes, Tumor promoter, Tumor suppressor.

car·ci·no·gen·e·sis

(kahr'si-nō-jen'ĕ-sis)
The origin, production, or development of cancer, including carcinomas and other malignant neoplasms.
[carcino- + G. genesis, generation]

carcinogenesis

The causation of cancer, whether CARCINOMA or SARCOMA.

carcinogenesis

production of cancer.

biological carcinogenesis
viruses and some parasites are capable of initiating neoplasia. See viral oncogenesis, Spirocercalupi.
chemical carcinogenesis
numerous chemicals have been identified as carcinogenic.
physical carcinogenesis
includes ultraviolet radiation, ionizing radiation and asbestos.
References in periodicals archive ?
sup][23] Furthermore, since high glucose can cause mutation and DNA mutation are believed to play an important role in carcinogenesis, [sup][24] it is logical to speculate that high glucose can promote cancer development.
9,10) A more indirect role for HIV in carcinogenesis has been suggested.
Estudios epidemiologicos en diferentes poblaciones y experimentales en animales de laboratorio, mantienen la hipotesis de que la cantidad y tipo de grasa de la dieta y composicion de los acidos grasos son factores determinantes en la carcinogenesis del colon.
We examined the effect of feeding cow ghee versus soybean oil on DMBA induced mammary carcinogenesis and on the expression on COX-2 and PPAR-[gamma] genes.
Many compounds that exhibited positive results in the in vitro assay have been shown to inhibit tumor promotion in the in vivo two-stage carcinogenesis test (Tanaka et al.
These data indicate that in spite of low or absent p16 expression, genetic alterations of the p16 and RB tumor suppressor genes are rare in endometrial carcinogenesis.
The CYP2A6 structure described here should facilitate the design and interpretation of more detailed mechanistic studies and the development of potent and selective compounds that reduce tobacco carcinogenesis and modify smoking behavior," the investigators said.
It appears that sucrose influences some parameters related to colon carcinogenesis, indicating that the acute repeated exposure to high concentrations of refined sugar is an additional risk factor for colon carcinogenesis, at least in rats.
The carcinogenesis sequence is viewed histologically as starting with tissue of normal appearance, followed by changes that lead to hyperplasia and dysplasia, of which the most severe forms are difficult to distinguish from carcinoma in situ.
Many epidemiological studies have linked EMF to carcinogenesis, implying an underlying genetic phenomenon mediated by EMF.
There is an urgent need for people to reduce risk factors involved in pancreatic carcinogenesis.