carboxypeptidase


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carboxypeptidase

 [kahr-bok″se-pep´tĭ-dās]
an exopeptidase that acts only on the peptide linkage of a terminal amino acid containing a free carboxyl group.

car·box·y·pep·ti·dase

(kar-bok'sē-pep'ti-dās),
A hydrolase that removes the amino acid at the free carboxyl end of a polypeptide chain; an exopeptidase.

carboxypeptidase

(kär-bŏk′sē-pĕp′tĭ-dās′, -dāz′)
n.
Any of several enzymes that catalyze the hydrolysis of the terminal amino acid of a polypeptide from the end that contains a free carboxyl group.

carboxypeptidase

Any enzyme (EC 3.4.16 to EC 3.4.18) which hydrolyses (cleaves) the peptide bond of the COOH terminal amino acid from a peptide; carboxypeptidase A removes aromatic or branched hydrocarbons, while carboxypeptidase B removes positively charged terminal lysine or arginine amino acid residues.

car·box·y·pep·ti·dase

(kahr-bok'sē-pep'ti-dās)
A hydrolase that removes the amino acid at the free carboxyl end of a polypeptide chain; an exopeptidase.

carboxypeptidase

an exopeptidase that catalyses the hydrolysis of amino acids in polypeptide chains from the C-terminal.
References in periodicals archive ?
Ephedra monosperma had mostly degradome proteins (profilins, desiccation-related protein, the GTP-binding protein RAN-1, and ceramidase) and had only two secretome proteins that we could detect in this initial comparative study--serine carboxypeptidase and glucan endo-1,3-[beta]-glucosidase.
"In this paper we link the catalytic activity of carboxypeptidase N to tumor progression in clinical samples from breast cancer patients and a breast cancer animal model," biomedical engineer Dr Tony Hu, who led the project, (http://medicalxpress.com/news/2013-11-early-stages-breast-cancer-blood.html) said in a news release.
(2007): <<Isolation, characterization and cDNA cloning of a novel bifunctional inhibitor of metallo carboxypeptidase and serine proteases isolated from the annelid Sabellastarte magnifica>>, Revista Cubana de Quimica, vol.
Angiotensin-converting enzyme (ACE, EC 3.4.15.1, dipeptidyl carboxypeptidase) is associated with the regulation of blood pressure and maintenance of salt and water homeostasis of the body [5].
(8) The thiol groups of CK are susceptible to oxidation, CK may be glycated, and it can be deactivated by the plasma enzyme carboxypeptidase N (summarised in Delanghe and De Buyzere (8)).
Results of BLAST search performed with human EGF against the non redundant mycobacterial protein database at NCBI Accession Protein Name E-Value Number NP_302390 Probable multidrug resistance pump 0.022 NP_301513 GTP-binding protein LepA 0.40 NP_301554 Putative -alanyl-D-alanine carboxypeptidase 2.2 NP_302118 heat shock protein 90 2.4 NP_302586 UDP-N-acetylenolpyruvoylglucosamine reductase 4.4 NP_301491 6-phosphogluconolactonase 6.5 NP_301739 Possible ATP/GTP-binding protein 7.8 NP_301890 Mycocerosic acid synthase 8.8 Table 3.
An intramolecularly quenched fluorescent tripeptide as a fluorogenic substrate of angiotensin-I-converting enzyme and of bacterial dipeptidyl carboxypeptidase. Eur.
Carbonic anhydrase was the first discovered zinc metalloenzyme; other enzymes include: carboxypeptidase, alkaline phosphatase, DNA/RNA polymerase and superoxide dismutase.
Tomato fruit carboxypeptidase: Properties, induction upon wounding, and immunocytochemical localization.
Miami Beach -- Mast cell carboxypeptidase shows promise as a new clinical marker for anaphylaxis, Dr.
Using a pair of specific monoclonal antibodies, CA4 and CA5, British researchers have developed an enzyme-linked immunosorbent assay for carboxypeptidase, a protease that is released with tryptase by activated mast cells and is a mediator of inflammation.
Amin I, Jinap S, Jamilah B (1998) Proteolytic activity (aspartic endoproteinase and carboxypeptidase) of cocoa bean during fermentation.