CES3

(redirected from carboxylesterase 3)

CES3

A gene on chromosome 16q22.1 that encodes a carboxylesterase which plays a role in detoxifying xenobiotics (e.g., cocaine and heroin) and in activating ester and amide prodrugs. It is primarily expressed in the intestine and liver.
References in periodicals archive ?
(b) Gene symbol (c) Gene name (c) 2 PPM [O.sub.3] J03933 Thrb thyroid hormone receptor beta, c-erbA-[beta] U73174 Gsr glutathione reductase L08447 Cd3z T-cell receptor CD3 zeta subunit L46791 Ces3 liver carboxylase precursor 10 (carboxylesterase 3) J02650 Rpl19 60S ribosomal protein L19 X96394 Abcc1 multidrug resistance protein D29766 Bcar1 FAK substrate p130 U49062 Cd24 signal transducer CD24 D16554 Ubb polyubiquitin 5 PPM [O.sub.3] X17163 Jun c-jun AP1 M84203 Kcnc2 potassium channel protein (KshIII A) D10862 Id1 inhibitor of DNA binding 1 M81855 Abcb1 multidrug resistance protein 1 D14051 Nos2 inducible nitric oxide synthase U45965 Cxc12 Mip-2 chemokine ligand 2 M86389 Hspb1 heat shock 27 kDa protein 1 L29232 1jf1r IGF-1 receptor D16237 Cdc25b M-phase inducerphosphatase 2 Accession no.
Real-time RT-PCR also suggests that carboxylesterase 3 (CES3) was down-regulated by AhR ligands.