CES1

(redirected from carboxylesterase 2)

CES1

A gene on chromosome 16q22.2 that encodes a member of the carboxylesterase family, which hydrolyse or transesterify xenobiotics (e.g., cocaine and heroin) and endogenous substrates with ester,
thioester or amide bonds. CES1 may participate in fatty acyl and cholesterol ester metabolism, and may play a role in maintaining the blood-brain barrier. It is the major liver enzyme and functions in liver drug clearance.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
McLeod, "Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan," Clinical Cancer Research, vol.
Li et al., "Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2," Fitoterapia, vol.