carboxyhemoglobin


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carboxyhemoglobin

 [kahr-bok″se-he´mo-glo″bin]
hemoglobin in which the sites usually bound to oxygen are bound to carbon monoxide molecules; carbon monoxide has an affinity for hemoglobin over 200 times that of oxygen. See carbon monoxide poisoning.

car·box·y·he·mo·glo·bin (HbCO),

(kar-bok'sē-hē'mō-glō'bin),
A fairly stable union of carbon monoxide with hemoglobin. The formation of carboxyhemoglobin prevents the normal transfer of carbon dioxide and oxygen during the circulation of blood; thus, increasing levels of carboxyhemoglobin result in various degrees of asphyxiation, including death.

carboxyhemoglobin

(kär-bŏk′sē-hē′mə-glō′bĭn)
n.
The compound that is formed when inhaled carbon monoxide combines with hemoglobin, binding more tightly than oxygen and rendering the hemoglobin incapable of transporting oxygen.

carboxyhemoglobin

Haemoglobin (Hb) with irreversibly bound carbon monoxide (COHb). COHb levels reflect CO exposure, which increases in fires and with exposure to car exhaust; Some COHb occurs naturally as a product of Hb catabolism and due to increased turnover of Hb in newborns, coupled with reduced efficiency of the infant’s respiratory system, leading to increased COHb.

Carboxyhaemoglobin levels
• < 2%: Non-smokers;
• 2%–12%: Smokers;
• > 20%: Toxic;
• > 50%: Lethal.

carboxyhemoglobin

COHb Hb in which carbon monoxide–CO is irreversibly bound

car·box·y·he·mo·glo·bin

(kahr-bok'sē-hē'mŏ-glō'bin)
A stable union of carbon monoxide with hemoglobin. The formation of carboxyhemoglobin prevents the normal transfer of carbon dioxide and oxygen during the circulation of blood; thus, increasing levels of carboxyhemoglobin result in various degrees of asphyxiation, including death.
Synonym(s): carbon monoxide hemoglobin, carboxyhaemoglobin.

Carboxyhemoglobin (COHb)

Hemoglobin that is bound to carbon monoxide instead of oxygen.
References in periodicals archive ?
BMI (body mass index): m/cm2; PEF (peak expiratory flow): L/min; Sat[O.sub.2] (peripheral oxygen saturation): %; heart rate: bpm; COex (exhaled CO): ppm; COHb (carboxyhemoglobin): %.
The aim of our study was to investigate the relation of blood carboxyhemoglobin (COHb) level with the findings and clinical properties at presentation and to elucidate the neurological and cardiological findings which are indicators of tissue hypoxia.
Carboxyhemoglobin levels were increased in the two patients who were heavy smokers.
Carboxyhemoglobin levels in children with nonspecific flu-like symptoms.
Israilova in the certificate of authorship No 4807122/14 "Fetal hypoxia model" by the content of carboxyhemoglobin and acid-base balance profile.
In 2005, Masimo introduced rainbow[R] SET Pulse CO-Oximetry technology, allowing noninvasive and continuous monitoring of blood constituents that previously required invasive procedures, including total hemoglobin (SpHb[R]), oxygen content (SpOC), carboxyhemoglobin (SpCO[R]), methemoglobin (SpMet[R]), and Pleth Variability Index (PVI[R]), in addition to SpO2, pulse rate, and perfusion index (PI).
Cooximetry uses four wavelengths of light to measure the absorptive characteristics of oxy- and deoxyhemoglobin, methemoglobin, and carboxyhemoglobin species.
Animal studies also revealed that tea filters could significantly reduce the acute toxicity, mutagenicity, lung damage and carboxyhemoglobin (COHb) levels in the blood caused by cigarette smoking.
In that instance, it was uptodate.com that I relied upon to secure our hyperbaric team and dissociate the patient's carboxyhemoglobin using our diving chamber.
The fingertip device uses light that is shined through the patient's nail bed to measure carboxyhemoglobin (blood poisoned by carbon monoxide) and methemoglobin (blood altered by other substances such as nitrogen dioxide).
The orders call for immediate administration of 100% high-flow oxygen (to be continued for at least 4 hours in patients with exposure) and for the use of venous blood gas sampling to determine carboxyhemoglobin values, even in asymptomatic patients.
In winter, consider carbon monoxide poisoning and test for carboxyhemoglobin. Carbon monoxide poisoning from poorly maintained heaters will often present as daily, diffuse, nocturnal headaches that clear up in the morning when patients get out into the fresh air.