A high level of carboxyhaemoglobin
is found in active smokers and passive smokers and that it persists longer than was previously thought after each tobacco intake resulting in chronic hypercarboxyhaemoglobinaemia, which greatly influences placental coefficient.
When carbon monoxide combines with haemoglobin it forms carboxyhaemoglobin
and methaemoglobin which reduces the oxygen-carrying capacity of the blood and can result in hypoxic stress (Alp et al 2006).
is bright red and most pulse oximeters cannot distinguish between it and oxyhaemogtobin, producing falsely high readings.
Sample pre-treatment for CO-oximetric de ermina ion of carboxyhaemoglobin
in pu refied blood and cavi y fluid.
Introduction of CO which has over 240 times greater affinity for joining with haemoglobin than oxygen, causes creation of carboxyhaemoglobin
(COHb), which renders the transport of [O.
Carbon monoxide exposure results in increased carboxyhaemoglobin
, leading to a reduction in placental oxygen delivery, and causes low birth weight and an increase in perinatal death.
One of the problems encountered in measuring oxyhaemoglobin, were the small errors arising from other pigments in the blood, including methaemoglobin, carboxyhaemoglobin
and sulfhaemoglobin, as well as reduced haemoglobin.
Further tests carried out on one blood sample, showed the presence of drugs such as Fluoxetine, known as Prozac and other related breakdown products, and Albendazole, an active ingredient in medication prescribed for the treatment of worms, as well as a high level of carboxyhaemoglobin
, an indicator of a large amount of carbon monoxide in the blood.
This dose equivalence is consistent with the reported three to fivefold greater levels of carboxyhaemoglobin
(a marker of carbon monoxide exposure) and tar inhaled when smoking a cannabis joint compared with a tobacco cigarette of the same size.
The high concentration of oxygen you breathe in helps the body make oxyhaemoglobin quickly and replace carboxyhaemoglobin
There were no major differences in the certified cause of death, extent of burns or carboxyhaemoglobin
concentrations in older or younger victims.