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A stable union of carbon monoxide with hemoglobin. The formation of carboxyhemoglobin prevents the normal transfer of carbon dioxide and oxygen during the circulation of blood; thus, increasing levels of carboxyhemoglobin result in various degrees of asphyxiation, including death.
Synonym(s): carbon monoxide hemoglobin
carboxyhaemoglobin The stable compound formed between CARBON MONOXIDE and HAEMOGLOBIN that does not readily dissociate. As a result, the oxygen carrying power of the blood is limited. A high level of carboxyhaemoglobin is the cause of death in carbon monoxide poisoning as from car exhaust.
carboxyhaemoglobin a stable compound produced when carbon monoxide combines irreversibly with HAEMOGLOBIN in the red blood cells, giving the blood a bright red colour. A consequence of the reaction is that haemoglobin is less able to combine freely with oxygen. This can lead to poisoning by lack of oxygen in the blood and eventually death if there is sufficient carbon monoxide in the atmosphere.