C terminus

(redirected from carboxy terminus)

C ter·mi·nus

the end of a peptide or protein having a free carboxyl (-COOH) group.

C terminus

The end of a polypeptide chain, which has a free (unattached) carboxyl (COOH) group.

C ter·mi·nus

(tĕr'mi-nŭs)
The end of a peptide or protein having a free carboxyl (-COOH) group.
References in periodicals archive ?
Most studies on TGF-[beta] signaling have concentrated on the canonical Smad pathway, whose result is the direct phosphorylation of 2 serine residues on the carboxy terminus of receptor-regulated Smads (R-Smads) (Smad2 and Smad3).
The CO genes encode proteins with two highly conserved regions: two B-box domains at the amino terminus and a CCT (CO, CO-like, and TOC1) domain near the carboxy terminus. The B-box region has been implicated in protein-protein interactions, and the CCT domain is a nuclear localization signal (Borden, 1998; Strayer et al., 2000; Torok et al., 2000; Robson et al., 2001; Khanna et al., 2009).
Like all NMDAR subunits, G1uN2A and GluN2B subunits consist of three basic parts: an extracellular amino region, a series of four transmembrane (TM) segments with connecting extracellular and intracellular loops, and an intracellular carboxy terminus (Fig.
We identified 2 monoclonal antibodies that reacted with amino terminus (26A1) and carboxy terminus (48A1) of EL among 15 clones.
Large Scale Biology Corporation (Vacaville, CA) has patented galactosidase truncated at the carboxy terminus and the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequences of human or animal lysosomal enzymes in a plant expression system.
The membrane M protein carboxy terminus binds to transmissible gastroenteritis coronavirus core and contributes to core stability.
This antibody was raised against an epitope mapping the carboxy terminus of ERK-2-encoded MAP kinase p42 of rat origin.
ERK-2 was directed against an epitope mapping at the carboxy terminus of ERK-2-encoded MAP kinase p42 of rat origin.
The amidation of the carboxy terminus has been reported to protect against carboxypeptidases (26), and exoprotease resistance was characteristic to designated "second-generation" reporter peptides (Table 1).
We have seen only certain desmoplakin sequences near its carboxy terminus, which you have predicted project far into the cytoplasm.
Mutations in the APOB gene causing the production of a truncated molecule can cause FHBL and hypocholesterolemia, whereas defects in the carboxy terminus of the LDL-receptor-binding domain of apoB cause FDB, a form of hypercholesterolemia.
The MAP2 antibody, clone AP20, has only recently been mapped to a carboxy terminus encompassing amino acids 997-1332 (L.