C terminus

(redirected from carboxy terminal)

C ter·mi·nus

the end of a peptide or protein having a free carboxyl (-COOH) group.
Farlex Partner Medical Dictionary © Farlex 2012

C terminus

The end of a polypeptide chain, which has a free (unattached) carboxyl (COOH) group.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

C ter·mi·nus

(tĕr'mi-nŭs)
The end of a peptide or protein having a free carboxyl (-COOH) group.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
These fragments share an RFamide at the carboxy terminal. Kisspeptinis expressed in the hypothalamus, arcuate nucleus, gonads, placenta, liver and pancreas.
Blood sample was collected for measurement of Apelin-13, Procollagen type-I N propeptide (PINP) and Cross-linked carboxy terminal telopeptide of type-I collagen (ICTP), and BMD was tested with a dual-energy X-ray absorptiometry scanner.
Radioimmunoassay for the pyridinoline cross-linked carboxy terminal telopeptide of type I collagen: a new serum marker of bone collagen degradation.
Ang I, in turn, is hydrolyzed at its carboxy terminal by angiotensin converting enzyme (ACE), which is present within the endothelium of most blood vessels, to form the active octapeptide angiotensin II (Ang II).
Monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) provide an important means of examining keratin expression in epidermal tumors and keratinizing disorders [15].
Current recommendation for the standardization of BTM measurements in future studies is to use serum carboxy terminal telopeptide of collagen type I (s-CTX) as the standard bone resorption marker and serum procollagen type I N-terminal propeptide (P1NP) as the standard bone formation marker [4].
While NMDARs have been reported to be synaptic or perisynaptic, developmental replacement of G1uN2B by GluN2A at hippocampal synapses (Barria and Malinow, 2002) depends on the match between the cytoplasmic carboxy terminal domain of GluN2 and the predominant MAGUK expressed at a given postnatal age (Sheng, 2001; Kiihr, 2006).
Confirmation of Peptan benefits on bone health was obtained by the measures of Carboxy Terminal Telopeptide (CTX), a usual marker of bone resorption.
Endoproteases of the Subtilisin-like Proprotein Convertase (SPC) family cleave substrate proproteins on the carboxy terminal side of a conserved sequence described as N-Arginine-X-X-Arginine-C.
The presence of P2X7 receptors on [GH.sub.4][C.sub.1] cells was additionally supported by the immunostaining of Western transfers of [GH.sub.4][C.sub.1] cell membranes using an antibody specific to the unique carboxy terminal domain of the P2X7 receptor.
Subsequently, a PCR assay (PCR 2) was developed using a commercially available primer and a virus-specific primer which amplified a fragment of ~600 bp that covered both the carboxy terminal of the viral coat protein and the 3' UTR of the virus.
The cleavage motif was modified with a carboxy terminal 6xHis-tag (Table 1) to enable the selective extraction of cleaved reporter peptide fragments from serum specimens (15).