carbonate dehydratase


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car·bon·ic an·hy·drase

a zinc-containing enzyme that catalyzes the interconversion of CO2 with HCO3- and H+. There are at least seven human isozymes that appear predominantly in red blood cells, secretory tissues, and muscle. A deficiency of carbonic anhydrase II can result in osteopetrosis and metabolic acidosis. The inhibition of carbonic anhydrase IV and possibly carbonic anhydrase II by sulfonamides is a current therapy in the treatment of glaucoma.

carbonate dehydratase

carbonate dehydratase

Carbonic anhydrase (see there), which is widely preferred in the working biomedical palance; cabonate dehydratase is the term preferred by the International Union of Biochemistry and Molecular Biology (IUBMB).