carbon tetrachloride


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Related to carbon tetrachloride: Carbon tetrachloride poisoning

carbon tetrachloride

 
a clear, colorless, mobile liquid used as a solvent. The most common route of poisoning is by inhalation of its vapors; it can also be absorbed through the skin. Toxicity results from depression of central nervous system activity and degeneration of the liver and kidneys. Signs of acute poisoning include nausea, vomiting, diarrhea, headache, and in severe cases anuria that can be fatal. Since the toxic concentrations are below the odor threshold, carbon tetrachloride should always be used in a well-ventilated area.

car·bon tet·ra·chlo·ride

a colorless, mobile liquid having a characteristic ethereal odor resembling that of chloroform; it is used as a cleansing fluid and as a fire extinguisher, and has been used as an anthelmintic, especially against hookworm.
Synonym(s): tetrachloromethane

carbon tetrachloride

A volatile liquid used as a solvent and cleaning agent (dry cleaning), and in fire extinguishers and refrigerants.

Toxicity
Toxic to the CNS, liver and kidneys; may cause coma or death.

carbon tetrachloride

CCl4 Toxicology A volatile liquid used in dry cleaning and fire extinguishers

car·bon tet·ra·chlo·ride

(kahrbŏn tet-ră-klōrīd)
A colorless, mobile liquid having a characteristic ethereal odor resembling that of chloroform; used as a cleansing fluid and as a fire extinguisher.
Synonym(s): tetrachloromethane.
References in periodicals archive ?
Oxidative damage to the lipids and proteins in the lungs, testis and kidney of rats during carbon tetrachloride intoxication.
Thereby, we hypothesized that SBE also employed the hepatoprotective effect in liver injury induced by carbon tetrachloride administration in mice.
Carbon tetrachloride levels were increased: 64.3 [+ or -] 7.17 [micro]mol/mg tissue; p < 0.050, compared with the control and supplemented groups.
The pet-ether and carbon tetrachloride soluble partitionates were separately chromatographed over silica gel (Kiesel gel 60H mesh 70-230) and the columns were eluted with pet-ether followed by mixtures of pet-ether and ethyl acetate in order of increasing polarities.
Carbon tetrachloride has been extensively used for decades to explore the response of liver toxicity since injury caused by this hepatotoxin replicate those seen in most cases of human liver diseases which makes it a reliable model to study both signal transduction and cell cycle events in vivo (Zoo 2000; Brennan 1998).
Antibacterial activity was also assayed with kanamycin and various extracts (crude ethanol extract, n-hexane soluble fraction, carbon tetrachloride soluble fraction) of the whole plant of A.
Group 1 was administered the plant extract only group 2 was administered plant extract and carbon tetrachloride group 3 was administered solvent only (corn oil) group 4 was administered solvent and carbon tetrachloride group 5 was administered vitamin E only group 6 was administered vitamin E and carbon tetrachloride and group 7 was untreated control.
Studies have shown an increased activation of NF-[kappa]B through oxidative stress induced by carbon tetrachloride in liver injuries [19, 20].
The rhizomes of Costus speciosus, which are occasionally used by the practitioners along with leaves of Centella asiatica for treatment of jaundice, has also been shown to have protective effects on carbon tetrachloride induced hepatotoxicity in rats (Verma and Khosa, 2009).
Chloroform and carbon tetrachloride, sometimes used as inert substances, are toxic to liver and central nervous system.
This sensor can detect acetone, chloroform, cyclohexane, N,N-dimethylformide, ethanol, ethyl acetate, hexane, methanol, carbon tetrachloride, tetrahydrofuran, and toluene.