carbohydrate-deficient transferrin


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carbohydrate-deficient transferrin

,

CDT

A serum protein used as a clinical marker of occult alcohol abuse. Frequent heavy use of alcohol depletes transferrin of carbohydrate moieties that are normally attached to it.
References in periodicals archive ?
Harmonization of measurement results of the alcohol biomarker carbohydrate-deficient transferrin by use of the toolbox of technical procedures of the International Consortium for Harmonization of Clinical Laboratory Results.
The diagnostic accuracy of carbohydrate-deficient transferrin, sialic acid and commonly used markers of alcohol abuse during abstinence.
Development and multicenter evaluation of the N Latex CDT direct immunonephelometric assay for serum carbohydrate-deficient transferrin. Clin Chem.
Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: a study in patients with alcohol dependence and liver disorders of non-alcoholic and alcoholic origin.
Carbohydrate-deficient transferrin as a measure of immoderate drinking: Remaining issues.
Case studies of the utility of serum carbohydrate-deficient transferrin (%CDT) in the clinical management of alcoholics.
Longitudinal comparison of carbohydrate-deficient transferrin and gamma-glutamyl transferase: complementary markers of excessive alcohol consumption.
Carbohydrate-deficient transferrin is elevated in 80% of individuals who have been drinking heavily within the past week.
This test measures the levels of a particular glycoprotein, carbohydrate-deficient transferrin, via a method called isoelectric focusing.
recently reported on their efforts toward the harmonization of carbohydrate-deficient transferrin (CDT) measurements in serum (1).
It was postulated that the diagnosis of alcohol use disorders could be markedly improved by a more systematic use of specific questionnaires and laboratory tests, including blood ethanol, serum GGT, carbohydrate-deficient transferrin CDT, and MCV.
The most widely used indirect biomarkers in the United States are carbohydrate-deficient transferrin (CDT) and the early detection of alcohol consumption (EDAC) test.

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