carbogen


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car·bo·gen

(kar'bō-jen),
A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.
[carbon dioxide + oxygen]

carbogen

An inhalant of O2 and CO2. Meduna’s original formulation called for 30% CO2 and 70% O2, but the term has been genericised and now refers to any CO2 concentration from 1.5% to 50%. The brain responds to increased CO by increasing breathing and heart rates.

Fringe psychiatry
Carbogen was used in psychedelic therapy in combination with LSD, psilocybin, DMT and 2C-B to ensure a smoother, more profound experience; hallucinogenic psychotherapy remains outside of mainstream medicine.
  
Oncology
The carbogen used in oncology is a mixture of 95% O2 and 5% CO2 and inhaled as a therapeutic adjunct, based on the premise that because tumours thrive in hypoxic conditions, increasing tumour oxygenation during radiotherapy or chemotherapy should increase tumour susceptibility to the therapy. It is considered investigational and is not reimbursed by BlueCross and BlueShield.

Psychiatric history
Meduna used carbogen to assess whether to manage patients with psychotherapeutics; those who reacted poorly to the altered state of consciousness induced by carbogen were de-selected for psychotherapeutic drugs, given the concern that they might evoke a similar response.

car·bo·gen

(kahr'bō-jen)
A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.
[carbon dioxide + oxygen]
References in periodicals archive ?
This solution was continuously oxygenated with carbogen gas (95% [O.sub.2] + 5% C[O.sub.2]) throughout the experiment starting at least 30 minutes prior to obtaining the brain slices.
Johnson held positions as director for the high potency division of Dishman Group's Carbogen Amcis operation, headquartered in Basel and as business manager for the strategic marketing of the oncology portfolio of Italy's UQUIFA.
The increase in blood flow in nonsmokers due to carbogen respiration was found in comparison to the relatively stable blood flow in smokers.
9 and glucose 11.1; pH 7.5 at 37 [degrees]C) and constantly aerated by carbogen (95% [O.sub.2] - 5 % C[O.sub.2]), while control samples were exposed to Tyrode alone (n = 3-5 per group) at same conditions.
The skull cavities were washed with synthetic interstitial fluid (SIF) containing (in mM): 120 NaCl, 5 KCl, 2 Ca[Cl.sub.2], 1 Mg[Cl.sub.2], 11 glucose, 1 NaHP[O.sub.4], 24 NaHC[O.sub.3], continuously gassed with carbogen (95% [O.sub.2] and 5% [CO.sub.2]), equilibrating the solution at pH 7.4 at room temperature.
Carbogen therapy is one of them which acts by inhalation, increases arterial oxygen saturation and maximises oxygen supply to the inner ear.
Carbon dioxide is liquid, the highest grade, a calibration gas mixture of co2 (5.9% +/- 0.1) + o2 (5.45% +/- 0.05) + n2 (88.65%), calibration gas mixture co (0.26%) + he (9.0%) + air, calibration gas mixture co (0.26%) + he (9.0%) + air, carbogen
The most frequently used gas is carbogen (95% [O.sub.2] and 5% C[O.sub.2]) as described in Kietzmann's model (Kietzmann et al., 1993).
The jejunum was cut into equal segments, flushed with normal saline to remove the contents, and then immersed in ice-cold Krebs solution that was pregassed with carbogen. Each segment was inverted by gently pushing a notched glass rod through the whole length of the intestine and then filled with 1 ml of Krebs solution.
separated a hypoxic and a normoxic mammary carcinoma group based on the median [[sup.18]F]FAZA TBR, although in this study, intertumoral oxygenation heterogeneity was increased by exposing some of the animals to carbogen breathing prior to [[sup.18]F]FAZA scanning and radiotherapy [4].
Full urinary bladder and ileum were carefully removed from the abdomen, then placed in cold Kreb's solution (118 mM NaCl, 4.7 mM KCl, 25 mM NaHC[O.sub.3], 1.15 mM Na[H.sub.2]P[O.sub.4], 2.5 mM Ca[Cl.sub.2], 1.1 mM Mg[Cl.sub.2], and 5.6 mM glucose), equilibrated with a carbogen mixture (95% [O.sub.2], 5% C[O.sub.2]) [32].
Kronenberg, "Steroids, carbogen or placebo for sudden hearing loss: a prospective doubleblind study," European Archives of Oto-Rhino-Laryngology, vol.
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