carbimazole


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carbimazole

An antithyroid drug that interferes with the production of thyroid hormone and is used in the treatment of HYPERTHYROIDISM. A brand name is Neo-Mercazole.
References in periodicals archive ?
The equal effectiveness in inducing euthyroidism of low daily dose OD-MMI and DD-MMI regimens observed in this study was similar to the results of previous studies that used either high daily dosage or unequal daily dosage of MMI or carbimazole, a prodrug of MMI, in comparison between OD-MMI and DD-MMI regimens.
She had pre-existing GD and was thyrotoxic, and treated with a high dose of carbimazole.
In a third case, a woman was treated with fenofibrate for acute pancreatitis due to hyperlipidemia and with carbimazole for Graves' disease.
The recommended therapy for GD during pregnancy is administration of ATDs (propylthiouracil, methimazole or carbimazole).
Effects of antithyroid drug carbimazole on the fertility and testicular structure of balb/c mice.
She had been on tablets propranolol and carbimazole for hyperthyroidism.
Some drugs are associated with positive ANCA results with or without clinical vasculitis, such as propylthiouracil, methimazole, and carbimazole. (5-7)
(2012) studied the effect of selenium (the sesame antioxidant) on carbimazole induced histopathological and histochemical alterations in prostate of albino rats and revealed that selenium treatment could ameliorate the toxicity induced by carbimazole in prostate gland.
In this case, the treatment entails intake of medicines such as: methimazole or carbimazole, or in other cases radioactive iodine treatment to ablate the gland, or even surgery.
Zenker et al., "Carbimazole is an inhibitor of protein synthesis and protects from neuronal hypoxic damage in vitro," Journal of Pharmacology and Experimental Therapeutics, vol.
(19) Pre-operative investigations in such patients must include preparation of red bloOd suspension (440~1200 ml), 2D Echo of Cardia, renal function tests, pulmonary function tests and administration of Carbimazole, iodine and propranolol to maintain the heart rate less than 90 /minute and BMR at < 20~30%.
Carbimazole was prescribed at 20 mg 8-hourly, and on the development of a skin reaction the dose was decreased to 10 mg 8-hourly.