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carbapenemase-resistant EnterobacteriaceaeA plasmid-transferrable beta-lactamase carried by an increasing number of strains of Klebsiella pneumoniae as well as other Enterobacteriaceae. Hydrolysis of the beta-lactam ring renders many of the antibiotics—in particular extended spectrum cephalosporins and carbapenems (imipenem, meropenem, and ertapenem)—ineffective.
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