carbapenem


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carbapenem

(kahr-bă-pen'em),
Member of a class of antibiotic drugs that works by inhibiting cell wall synthesis.
Farlex Partner Medical Dictionary © Farlex 2012

carbapenem

(kär′bə-pĕn′əm)
n.
Any of several semisynthetic or synthetic beta-lactam antibiotics that are used chiefly to treat serious infections caused by bacteria that are resistant to other antibiotics.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

carbapenem

A class of antibiotics with a broad spectrum of action against gram-positive, gram-negative, and anaerobic germs. The carbapenems include imipenem and meropenem.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Scientists identified a small number of genes that can cause resistance to carbapenem antibiotics when expressed.
Over the previous couple of years, Metallo-beta-lactamase producing Gram Negative Rods are being notifiable with the increasing frequency from various parts of the world and they seems as a most generally circulated and have carbapenem resistance mechanism.
[Bla.sub.IMP] and [bla.sub.VIM] mediated carbapenem resistance in Pseudomonas and Acinetobacter species in India.
Multiple studies have reported carbapenem resis-tance from Pakistan7,8.
Pseudomonas aeruginosa (18%) showed highest susceptibility of 87% Sensitivity to Cefepime Tazobactam, Cefepime, Carbapenem and Amikacin followed by 70% Sensitivity to Piperacillin Tazobactam and Cefoperazone sulbactam.
polymyxin B combined with a carbapenem was not more effective than monotherapy in carbapenem-resistant Gram-negative bacterial infections.
One of the limitations of this study is that the result was not verified with molecular techniques, as the main aim of the study was to present data on the carbapenem resistance among Gram negative bacteria.
Although the determination of carbapenem MIC breakpoints suggested by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) is sometimes useful for predicting CP-GNB, some CP-GNB isolates remain susceptible or intermediate to many carbapenems.
According to the Centers for Disease Control and Prevention (CDC), the emergence and dissemination of carbapenem resistance among Enterobacteriaceae in the U.S.
aeruginosa from strains with other mechanisms responsible for carbapenem resistance.
Resistance to carbapenem was 174(79%) in Klebsiella pneumoniae and 14(5.4%) in Escherichia coli.