carbamoyl phosphate


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car·ba·mo·yl phos·phate

(kar'bă-mō-il fos'fāt),
A reactive intermediate capable of transferring its carbamoyl group to an acceptor molecule, forming citrulline from ornithine in the urea cycle and ureidosuccinate from aspartate in pyrimidine ring formation.
References in periodicals archive ?
Rayment, "Structure of carbamoyl phosphate synthetase: a journey of 96 a from substrate to product," Biochemistry, vol.
The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1.
Intestinal carbamoyl phosphate synthase I in human and rat: expression during development shows species differences and mosaic expression in duodenum of both species.
All the natural phospho-donors (acetyl phosphate, carbamoyl phosphate, phosphoramidate, and monophosphoimidazole) bind to active site with binding energy ranging from -3.32 to -3.93 kcal/mol and inhibition constant from 1.31 mM to 3.67 mM (Table 1).
OA detection in urine forms a useful surrogate marker of increased carbamoyl phosphate, a substrate of OTC (Fig.
OTCD patients have low blood citrulline because of reduced conversion from carbamoyl phosphate. Citrulline is one of the amino acids routinely measured in MS/MS newborn-screening programs.