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capreomycin/cap·reo·my·cin/ (kap″re-o-mi´sin) a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis ; used as the disulfate salt.
An antibiotic that is derived from a bacterium (Streptomyces capreolus) and is used in its sulfate form to treat tuberculosis.
an antibiotic and antitubercular agent.
indications It is prescribed in the treatment of pulmonary infections caused by capreomycin-susceptible strains of Mycobacterium tuberculosis when the primary agents are ineffective or cannot be used.
contraindications Known sensitivity to this drug prohibits its use. It must be used with caution in patients with preexisting renal or auditory impairment.
adverse effects Among the most serious adverse reactions are nephrotoxicity, hearing loss, tinnitus, vertigo, leukocytosis, leukopenia, urticaria, and skin rash.
capreomycinAn aminoglycoside-related cyclic peptide antibiotic used in combination with streptomycin and other agents to treat Mycobacterium avium complex and M tuberculosis.
Nephrotoxicity, ototoxicity and hearing loss, anorexia, thirst, excess urination, haematuria, anaemia.