Food and Drug Administration (FDA) convened its Clinical Chemistry and Clinical Toxicology Devices Advisory Panel, seeking guidance and recommendations on the acceptability of capillary specimens
in critically ill patients based on benefits and risks, and whether capillary specimen
testing in this patient population meets the criteria for waived status under the Clinical Laboratory Improvements Amendments (CLIA) regulations.
Among 50 facilities, 30 (60%) had a written procedure for routinely retesting critical POCG results using a venous blood specimen (n = 9), a new capillary specimen
(n = 8), both venous and capillary specimens
(n = 7), or either capillary or venous specimens (n = 6).
But it wasn't known if the test results from a capillary specimen
were an accurate reflection of a child's serum lead level.
Although POCG testing on capillary specimen
has the advantage of speed and convenience, it is also less accurate than serum glucose measurements performed by the clinical laboratory.
Serum bilirubin level, typically measured in a capillary specimen
obtained by performing a heel puncture, is critical in the management of neonatal jaundice.
What is the specimen volume required for closed tube, open tube, and capillary specimen
Redrawing might also be necessary to make sure that an arterial specimen is indeed arterial, or that a capillary specimen
from an infant is correctly drawn on ice, mixed, and immediately transported to the laboratory for blood gas analysis.
Cholesterol in fingerstick capillary specimens
can be equivalent to conventional venous measurements.
It brings nearly 100 plastinated specimens, among them entire animal bodies, body slices, organs and capillary specimens
to guide visitors on a journey through nature's anatomy.
Ancillary equipment available for experiments on BM16 includes a liquidhelium-cooled cryostat, for spinning capillary and flat-plate specimens down to 4.15 K, and below with pumping; a cold-nitrogen-gas blower for capillary specimens
in the range 80 K to 373 K; a hot-air blower for capillary specimens
up to 950 [degrees]C; a high-temperature oven for spinning flat-plate specimens up to 1600 [degrees]C in vacuum, and 1200 [degrees]C in an oxidizing atmosphere; a capillary cell for condensing volatile samples in situ, or for treatment of samples in different atmospheres or under vacuum; translation stages for mapping residual strain in engineering components.
For glucose determinations, the larger biological variance (C[V.sub.IC]) as well as analytical imprecision for capillary specimens
(C[V.sub.AC]) contributed to the larger total variance.
The tube has a pierceable cap, which allows it to be processed in the automated mode on hematology analyzers, thereby, minimizing laboratorians' hands-on time in processing capillary specimens