capillary gel electrophoresis


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capillary gel electrophoresis

A type of electrophoresis in which charged biomolecules (e.g., DNA) are separated by filling a capillary tube with a gel matrix, in which shorter strands of DNA migrate more quickly than longer strands. CGE can be used to identify single-base deletion products or truncated sequences from full-length nucleic acids by analysing inserted synthetic oligonucleotides.
References in periodicals archive ?
5 h, and the capillary gel electrophoresis of the pooled PCR products takes ~30 min), easy to perform, detects ~99% patients with macrodeletions and 89% with macroduplications, and identifies small insertions or deletions.
Capillary gel electrophoresis (CGE) in molecular pathology and genetics is an ideal instrument for fast, fully automated analysis.
Ultrasensitive near-IR fluorescence detection for capillary gel electrophoresis and DNA sequencing.
Capillary gel electrophoresis (CGE) has been used for analysis of double-stranded DNA, including products of PCR [1-5].