capacitation


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to capacitation: Acrosome reaction

capacitation

 [kah-pas″ĭta´shun]
the process by which the glycoprotein coat and the seminal proteins are removed from the surface of the sperm's acrosome by substances secreted by the uterus or fallopian tubes of the female genital tract, thereby permitting the acrosome reaction to occur.

ca·pac·i·ta·tion

(kă-pas'i-tā'shŭn),
Capacitation is a process whereby the glycoprotein coat is modified and seminal proteins are removed from the surface of the sperm. There are no morphologic changes. Capacitation also occurs in in vitro fertilization; after capacitation, the acrosomal reaction can occur.
[L. capacitas, fr. capax, capable of]

capacitation

A biochemical event in mammals that consists of the post-ejaculation maturation of sperm, which are capable of penetrating the zona pellucida and fertilising an oocyte. Capacitation is due to exposure to secretions—sterol binding albumin, lipoproteins, proteases and glycosidases—in the uterus, and requires the correct concentration of the tripeptide fertilisation promoting peptide, which is present in seminal fluid. Capacitation destabilises the acrosomal sperm-head membrane, facilitating binding of a sperm to the oocyte by removing steroids (e.g., cholesterol) and non-covalently bound seminal glycoprotein; the process is reversible and includes all of the events up to the acrosome reaction, which is irreversible.

capacitation

Reproductive medicine The postrelease maturation in sperm, which are capable of penetrating the zona pellucida and fertilizing an oocyte after exposure to secretions in the ♀ genital tract. Cf Acrosome reaction.

ca·pac·i·ta·tion

(kă-pas'i-tā'shŭn)
A conditioning process whereby the glycoprotein coat and seminal proteins are removed from the acrosome of a sperm. After capacitation has occurred, perforations develop in the acrosome.
[L. capacitas, fr. capax, capable of]

capacitation

changes occurring in SPERM while inside the female reproductive tract, where the acidic environment causes alterations to the cell membrane of the sperm that make possible its adhesion to the secondary OOCYTE.
References in periodicals archive ?
Pattern B, sperm cells exhibiting fluorescence at the acrosome and the middle sections, thus they were classified as undergoing capacitation. Pattern C: sperm cells displaying fluorescence on the head that was greater in intensity at the acrosomal zone, thus they were considered as undergoing acrosomal reaction.
Premature capacitation is known to occur in the seminal plasma, causing energy depletion of the sperm and decreasing the chance of fertilization; therefore, increasing the severity of capacitation within an appropriate timeframe should be beneficial for male fertility.
In this way, the microbiota does not present a problem to be solved, but the capacitation of a gut rhetoric to be lived--t he very grounding of thought, cognition, and response to the world.
Pearson correlation coefficients were calculated to determine the associations between capacitation status, variation of capacitation status, and litter size.
After capacitation, the levels of adiponectin and its receptors are lowered, suggesting a direct role on sperm motility.
The forms pre- and post-test, like the dynamics used in the capacitation, were planned and elaborated by the monitors with the preceptor in a shared manner, aiming the collaborative practice between the members of the team, the critical, creative thinking and a more effective action from the community health workers.
Although all doses of BPA dramatically decreased intracellular ATP levels (p < 0.05), other parameters--including viability, levels of intracellular ROS, LDH, [Ca.sup.2+], and capacitation status--were apparently unaffected (Figures 1 and 2).
Sperm Capacitation. Reduction in capacitated spermatozoa was observed in all treatment groups (Table 1).
Fernandez-Novell et al., "Oligomycin A-induced inhibition of mitochondrial ATP-synthase activity suppresses boar sperm motility and in vitro capacitation achievement without modifying overall sperm energy levels," Reproduction, Fertility and Development, vol.
Mrsny, "Taurine and hypotaurine: their effects on motility, capacitation and the acrosome reaction of hamster sperm in vitro and their presence in sperm and reproductive tract fluids of several mammals," Development, Growth & Differentiation, vol.
The reactive oxygen species interacted with the sperm plasma membrane for normal hyper-activation and capacitation of sperm; however, the higher concentration of antioxidants in extender blocked the normal physiological function of free radicals (Roca et al., 2004).