cap binding protein

cap binding protein

A protein that binds to the ends of messenger RNA molecules and helps to speed up protein synthesis on ribosomes.
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Because of its low availability, the cap binding protein eIF4E is the rate limiting factor and inhibitory proteins, namely, eIF4E binding proteins (4E-BPs), regulate this process by binding to eIF4E which prevents its association with eIF4G, thus inhibiting protein translation [3].
The eIF4 complex is composed of three polypeptides: eIF4E (the cap binding protein), eIF4A (an RNA helicase), and eIF4G (scaffolding protein).