Epidemiological trends in nosocomial
candidemia in intensive care.
Candidemia surveillance in the five-county Denver metropolitan area began in May 2017.
Candidemia is defined as the presence of the yeast in the bloodstream (2).
Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome.
COLOMBO, A.L., NUCCI, M., PARK, B.J., NOUER, S.A., ARTHINGTON-SKAGGS, B., MATTA, D.A., WARNOCK, D., MORGAN, J., and BRAZILIAN NETWORK
CANDIDEMIA STUDY, 2006.
A major controversy in the analysis of CVC removal on the outcome of patients with
candidemia is the time of CVC removal.
Long-term impact of an educational antimicrobial stewardship program on hospital-acquired
candidemia and multidrug-resistant bloodstream infections: a quasi-experimental study of interrupted time-series analysis.
Bloodstream Candida infections (
Candidemia) become detrimental in immune-compromised patients and those in intensive care unit (ICU).
auris
candidemia, Javier Peman, MD, said at the meeting.
Expressions of interest for Development and pilot testing of a framework for AMR surveillance in
candidemia and assist with further development of WHO Global antimicrobial resistance (AMR) Surveillance System.
Results: Nine (15%) patients had
candidemia. The mean serum PCT level was not significantly different between the patients with and without
candidemia at admission and 24, 48, and 72 h of the ICU stay (P > 0.05), but was significantly different on 7 and 14 days of the ICU stay (P < 0.001).
Candidemia is the main cause of fungal sepsis, therefore, preferred prophylactic antifungal therapy is commonly done with first generation Azoles such as Fluconazol and Polyenes (Amphotericin B), both with adequate penetration in central nervous system (CNS) and renal parenchyma.
