nanolipogel

(redirected from cancer smart bomb)

nanolipogel

A drug-delivery system consisting of nanoscale, hollow spheres made of a biodegradable, FDA-approved synthetic lipid, which can be loaded with an array of molecules. In early feasibility studies on melanomas, nanolipogel microspheres were loaded with transforming growth factor-beta and interleukin-2, and were biodegraded in vivo, resulting in neutralisation of the melanoma’s secretions and upregulation of the patient’s immune response.
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In an advance with major potential, scientists are refining ways to arm the protein missiles with radioactive or toxic substances that kill the tumor - creating the equivalent of cancer smart bombs.
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