cancer cell


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cancer cell

A malignant cell, which has several key features:
(1) Divide uncontrollably;
(2) Refuse to die—i.e., bypass programmed cell death (apoptosis); and
(3) Spread distally (matastasis) from original site via lymphatics or blood vessels.

cancer cell

A cell present in a neoplasm and differentiated from normal tissue cells because of its degree of anaplasia, irregularity of shape, nuclear size, changes in the structure of the nucleus and cytoplasm, increased number of mitoses, and ability to metastasize.
See also: cell
References in periodicals archive ?
Ogretmen studies how cancer cells are different than normal cells to understand how cancer grows and spreads in the body.
The pro-drug only becomes toxic in cancer cells because the virus infects them and not normal cells.
Early detection significantly increases the likelihood of survival, and much research is geared toward detecting cancer-prone and individual cancer cells long before a tumor forms.
A molecule that cells normally use to fight viruses is also involved in keeping cancer cells alive.
The ability of butyrate to trigger cancer cell apoptosis is one of the main features of its anticancer activity [160].
Wells says that although the re-emergence of E-cadherin makes cancer cells look "almost benign" that's just a "disguise." It might even protect cancer cells against elimination by chemotherapy agents that target rapidly proliferating cells.--J.R.
Both isomers stimulated MCF-7 human breast cancer cell proliferation to equivalent degrees at concentrations ranging from 0.32 to 1.6 [micro]M.
'Earlier, cancer researchers focused mostly on the cancer cells themselves, but now we understand that the interaction between the cancer cells and their environment is key to how cancer grows and spreads,' she notes.
Kinase inhibitors have been developed against PI3K as well, and by and large they do a lovely job of killing cancer cells in dishes.
Satoru Osuka, of the molecular neuro-oncology department of Emory University School of Medicine in Atlanta, Georgia, took special note of the anime's seventh episode titled 'Cancer Cell.' The episode had the show's cast of immune cells face off against a cancer cell that threatened to spread across the body they lived in, reports Nijimen via Anime News Network.
In contrast, high levels of 'good' cholesterol keeps integrins inside cells and may, therefore, protect against cancer cell spread.
Jou said that PSPC1 not only promotes cancer cell proliferation, but it also turns regular cells into mobile cells, promotes cancer metastasis, and even develops cancer stem cells that cause tumors and build resistance against cancer treatment drugs.

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