Family 2 is directed to cancer antigens
believed to be capable of stimulating anti-cancer immune responses.
8] Nonstandard abbreviations: CEA, carcinoembryonic antigen; PSA, prostate-specific antigen; CA125, cancer antigen
125; CA19-9, cancer antigen
19-9; BCG, bacille Calmette-Guerin; ADCC, antibody-dependent cell-mediated cytotoxicity; OC125, ovarian cancer 125; CA125II, heterologous double-determinant CA125 assay; FDA, US Food and Drug Administration; ROMA, risk of ovarian malignancy algorithm; HE4, human epididymis protein 4; PPV, positive predictive value; PLCO, Prostate, Lung, Colon, and Ovary Cancer (Screening Trial); TVS, transvaginal sonography; UKCTOCS, UK Collaborative Trial of Ovarian Cancer Screening; ROCA, Risk of Ovarian Cancer Algorithm; SPORE, Specialized Program of Research Excellence; CEACAM, CEA cell adhesion molecule; USPSTF, US Preventive Services Task Force.
This is the first milestone payment Corixa has received under the terms of a 1999 agreement with JT, which provides JT with certain rights to develop vaccine products containing Corixa's novel lung cancer antigens
, including antigens formulated using Corixa's microsphere delivery system and proprietary adjuvant technologies.
We are excited to enter this alliance with Agensys to generate fully human antibody candidates to their large portfolio of novel, clinically relevant cancer antigens
," stated R.
Prostate cancer detection in the "grey area" of prostate-specific antigen below 10 ng/ml: head-to-head comparison of the updated PCPT calculator and Chun's nomogram, two risk estimators incorporating prostate cancer antigen
A promising new prostate cancer marker, PCA3 (prostate cancer antigen
3), has recently become available, and its utility for predicting short-term biopsy progression has been studied in an active surveillance program (2).
MIAMI -- A test for circulating lysophosphatidic acid dramatically improves detection of early-stage ovarian cancer, compared with current screening methods dependent on cancer antigen
125, Yan Xu, Ph.
Its lead programme is an affinity enhanced T-cell therapy targeting the NY-ESO cancer antigen
4] Nonstandard abbreviations: PSA, prostate-specific antigen; EPCA-2, early prostate cancer antigen
2; S/N, signal-to-noise; EDRN, Early Detection Research Network.
125 (CA 125) (1-3) is commonly increased in liver cirrhosis and increased even more in ascitic fluid (4-6).
Thus, survivin is considered a major cancer antigen
Placental alkaline phosphatase and cancer antigen
125 in sera of patients with benign and malignant diseases.