NIAID said the HVTN 702 vaccine regimen consists of two experimental vaccines: a canarypox
vector-based vaccine called ALVAC-HIV and a two-component gpl20 protein subunit vaccine with an adjuvant to enhance the body's immune response to the vaccine.
, pigeonpox, penguinpox, quailpox (44), swinepox, sheeppox, goatpox, leporipoxviruses, and parapoxviruses exist (20,45).
Phylogenetic analyses based in both fragments grouped the flamingo isolate consistently within clade B2 of canarypox
This in turn led to a new trial (RV 144 in Thailand) to test a canarypox
vector vaccine (ALVAC-HIV) boosted with a recombinant glycoprotein vaccine (AIDSVAX B/E).
Polimorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type I infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox
Modified vaccinia ankara (MVA), canarypox
, adenovirus and adeno-associated virus (AAV) are among the commonly used vectors in HIV vaccines currently under clinical development.
Vaccine recipients received, over a 6-month period, four doses of a canarypox
virus that expresses the rabies virus glycoprotein has been licensed in the USA as a parenteral monovalent vaccine for cats and as a combination rabies vaccines for cats with feline panleukopenia virus, feline parvovirus, feline calicivirus vaccines included in the product (51).
The priming vaccine, Sanofi Pasteur's ALVAC-HIV, is a modified canarypox
ALVAC uses canarypox
, a bird virus altered so it can't cause human disease, to ferry synthetic versions of three HIV genes into the body.
Alvac uses canarypox
, a bird virus, altered so it can't cause human disease, to ferry synthetic versions of three HIV genes into the body.
Their topics include an immunological basis for the rational design of new vaccines, new approaches to immunization using the skin, veterinary applications of the canarypox
vaccine vector technology in domestic mammalian species, human papillomavirus, the current status of cancer vaccines, and antigen-specific immunotherapy for allergies.