More recently, we demonstrate how the transfer rates across sinusoidal and canalicular
membranes generate hepatocyte concentrations, and that the liver flow rates alter these concentrations by modifying Gd-BOPTA clearances across the sinusoidal membrane.
(1,3,4,10,20) Considering that canaliculotomy may lead to narrowing and scarring of the canalicular
lumen, lacrimal pump dysfunction, and canalicular
fistulas, some investigators recommend canalicular
curettage alone or with the less invasive procedure of canaliculoplasty.
Nos fetos com cinco meses de gestacao, os pulmoes estavam na fase canalicular
, com o septo conjuntivo formado por TC frouxo e vascularizado (Figura 1C).
(136) A few studies have demonstrated a canalicular
clusterin staining pattern in 54% to 75% of HCCs.
* 90.91% eyes had NLD block and 9.09% eyes had common canalicular
block in failed endonasal DCR cases.
This choleretic action of fibrates mainly bezafibrate was further attributed to enhancement in canalicular
membrane fluidity (opposing EE
Absence of a surface-connected canalicular
system in bovine platelets.
Bile acids account for this increase: They induce alkaline phosphatase synthesis and exert a detergent effect on the canalicular
membrane, allowing leakage into serum [126,134].
Proper management of canalicular
lacerations require thorough knowledge of the anatomy of the lacrimal drainage system, eyelids and periorbital structures, careful examination for associated ocular injury and prompt referral to a team of subspecialists when complicated lacerations are encountered.
Etiology Silicon Medpor tube coated tube (n = 8) (n = 11) Idiopathic canalicular
obstruction 4 7 Punctum agenesis 1 1 Functional obstruction secondary 0 1 to external DCR Canalicular
obstruction secondary 0 2 to ichthyosis Traumatic upper lacrimal system 1 0 damage Upper or middle lacrimal system 1 0 excision secondary to tumor surgery Upper or middle lacrimal system 1 0 damage secondary to multidiode laser DCR TABLE 3: The comparative advantages and disadvantages of both tubes.
ABCB4 codes for multidrug resistance protein 3 (MDR3), which transports phosphatidylcholine from the inside to the outside of liver cell canalicular
 The typical pattern of liver enzyme abnormality is mixed with moderate elevation of transaminases, but a far more significant rise in the canalicular