Camphorated phenol is among phenolic group of medicaments which have been applied either on a cotton wool pellet placed in the pulp chamber or on a paper point placed in the root canal, with the rationale being that the antimicrobial effect is delivered through vaporization of the medicament .
The aim of this study was to compare the effectiveness of various concentrations of nanosilver gel with 2% chlorhexidine gluconate and camphorated phenol on Enterococcus faecalis biofilm using methyl thiazolyl tetrazolium (MTT) assay and confocal laser scanning microscopy (CLSM) analysis.
The hypothesis tested was that nanosilver gel, chlorhexidine gluconate, and camphorated phenol are equally effective on Enterococcus faecalis biofilm.
Two tests were done (MTT assay and CLSM analysis) to determine the effectiveness of nanosilver gel, chlorhexidine gluconate, and camphorated phenol on E.
4) camphorated phenol (Hubei Taichen Janrui Pharmaceutical Co.
The colour of the biofilm changes from green to yellowish red, nanosilver gel being more yellowish red (in all 3 concentrations) compared to 2% chlorhexidine gluconate and camphorated phenol and more green for the control group indicating that almost all the cells are alive (Figures 1-6).
The current study shows that camphorated phenol has lower inhibition effect compared to nanosilver gel and 2% chlorhexidine gluconate which coincides with the finding when camphorated phenol was compared to calcium hydroxide .