The optimum proteolytic activity of calpains
was observed in the fresh meat of red deer - 0.085 um/h for one gram of protein (Fig.
Goll, "Changes in the calpains
and calpastatin during postmortem storage of bovine muscle," Journal of Animal Science, vol.
3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance," Neuromuscular Disorders, vol.
Conclusively, an uncontrolled activation of calpain
has been found to be implicated in the pathophysiology of several cardiovascular disorders  including myocardial IRI , and the inhibition of calpains
has been shown to attenuate myocardial stunning and reduce infarct size after ischemia reperfusion  (Figure 1).
Zhu, "The molecular mechanisms of calpains
action on skeletal muscle atrophy," Physiological Research, vol.
Kawashima, "Identification and Characterization of Membrane-Bound Calpains
in Clathrin-Coated Vesicles from Bovine Brain," European Journal of Biochemistry, vol.
mediate axonal cytoskeleton disintegration during Wallerian degeneration.
The non-significant improvement in texture in the BF muscle may be related to the low calpain
values (Koohmaraie, Seideman, Schollmeyer, Dutson & Babiker, 1988), as well as the high collagen level (Hildrum et al., 2009).
Proteinase (cathepsin B, D, L and calpains
) levels and conditioning rates in normal, electrically stimulated and high-ultimate pH chicken muscle.
Role of calpains
in postmortem proteolysis in chicken muscle.
Effect of [Ca.sup.2+] on Binding of the Calpains