calmodulin


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calmodulin

 [kal-mod´u-lin]
a calcium-binding protein present in all nucleated cells, thought to be an essential mediator of most calcium-sensitive cellular processes.

cal·mod·u·lin

(kal-mod'ū-lin),
A small, ubiquitous eukaryotic protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions. This calcium-protein complex binds to the apoenzyme, to form the holoenzyme, of certain phosphodiesterases; through these mechanisms, the complex regulates adenylate and guanylate cyclases, many kinases, phospholipase A2 activity, and other basic cellular functions.
[calcium + modulate]

calmodulin

(kăl-mŏj′ə-lĭn)
n.
A calcium-binding protein that mediates many metabolic processes, such as contraction of smooth muscle, by binding to enzymes and other proteins.

cal·mod·u·lin

(kal-mod'yū-lin)
A protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions.
[calcium + modulate]

cal·mod·u·lin

(kal-mod'yū-lin)
Protein that binds calcium ions.
[calcium + modulate]
References in periodicals archive ?
GenBank Species Strain Number Gene Aspergillus terreus CD72E1 KT427380 [beta]-Tubulin KT427386 Calmodulin Aspergillus sydowwi G70 KT427381 [beta]-Tubulin Paecilomyces lilacinus G41 KT427382 [beta]-Tubulin Paecilomyces lilacinus G42 KT427383 [beta]-Tubulin Diaporthe endophytica G13 KT427385 ITS KP2164961 Calmodulin Cladosporium sphaerospermum OB96E2 KP2164981 ITS Cladosporium cladosporides G28 KP2164971 ITS Fusarium solani CD34F1 KP2164951 ITS Table 5.
Neurogranin, a link between calcium/ calmodulin and protein kinase C signaling in synaptic plasticity.
Schulman, "Dual role of calmodulin in autophosphorylation of multifunctional cam kinase may underlie decoding of calcium signals," Neuron, vol.
The pineal hormone decreases the levels of ER[alpha] in MCF-7 cells [24] and destabilizes the estradiol-ER complex preventing its binding to estradiol-responsive promoters [25], likely through interaction with calmodulin bound to ER[alpha] [26, 27].
In our experiment, 4 myo-inositol-1-phosphate synthase genes and 3 calmodulin genes participated in the resistance to low temperature stress, and the expression of calmodulin genes continued to increase during low temperature treatment.
Munoz et al., "Molecular insights into the mechanism of calmodulin inhibition of the EAG1 potassium channel," Structure, vol.
Histologic evaluation of these hearts should reveal CBN associated with altered Ca++ metabolism, diffusion of calmodulin into the myocardium, and free radical production, which indicate the possibility of acute stress cardiomyopathy as the cause of death.
PDE1 was assessed in presence of cyclic GMP, in basal state (1 mM EGTA) and in a calmodulin-activated state (18 nM calmodulin with 10 [micro]M Ca[Cl.sub.2]).
Molecular interaction and functional regulation of connexin50 gap junctions by calmodulin. Biochem J 2011;435:711-22.
In addition, in Brassica oleracea, the activity of Gly I in leaf discs was inhibited in the presence of calmodulin inhibitors such as trifluoperazine (TFP), chlorpromazine (CPZ) and compound 48/80 in the cultures, which in turn significantly inhibited callus induction (Bagga et al., 1987; Hoque et al., 2016), indicating that calmodulin may activate Gly I activitiy.
Hund, "Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis," PLoS Computational Biology, vol.
The benzothiazoles also have immuno-suppressive, antiviral [18,19], and calmodulin (CaM) antagonists [20] activities.