calcium-sensing receptors, CaRs

calcium-sensing receptors, CaRs

Dimeric G-protein-coupled calcium receptors occurring on chief cells of the parathyroid gland; C cells of the thyroid gland; renal tubules; osteoclasts and osteoblasts; chondrocytes; epithelium of the stomach and proximal jejunum; and on colonic epithelium. CaRs are also expressed on many other tissues such as nerve, bone marrow, placenta, pituitary gland, pancreas, skin and breast.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005