calcium pump


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Related to calcium pump: plasma membrane calcium pump

pump

 [pump]
1. an apparatus for drawing or forcing liquid or gas.
2. to draw or force liquids or gases.
blood pump a machine used to propel blood through the tubing of extracorporeal circulation devices.
breast pump a pump for taking milk from the breast.
calcium pump the mechanism of active transport of calcium (Ca2+) across a membrane, as of the sarcoplasmic reticulum of muscle cells, against a concentration gradient; the mechanism is driven by hydrolysis of ATP.
enteral feeding pump an infusion pump specifically designed for administration of a solution through a feeding tube.
insulin pump see insulin pump.
intra-aortic balloon pump see intra-aortic balloon pump.
muscle pump compression of veins by the contraction of skeletal muscles, forcing blood towards the heart against the flow of gravity; seen particularly in the deep veins of the lower limbs. Called also venous pump.
proton pump a system for transporting protons across cell membranes, often exchanging them for other positively charged ions.
sodium pump (sodium-potassium pump) the mechanism of active transport driven by the energy generated by Na+,K+-ATPase, by which sodium (Na+) is extruded from a cell and potassium (K+) is brought in, so as to maintain the low concentration of sodium and the high concentration of potassium within the cell with respect to the surrounding medium. A high concentration of intracellular potassium is necessary for vital processes such as protein biosynthesis, certain enzyme activities, and maintenance of the membrane potential of excitable cells. Called also Na+-K+ pump.
stomach pump see stomach pump.
venous pump muscle pump.

cal·ci·um pump

a membranal protein that can transport calcium ions across the membrane using energy from ATP.

calcium pump

A calcium-pumping enzyme which is present in high concentrations (up to 90%) in the membrane of sarcoplasmic reticulum and activated by cATPase, which reduces cytoplasmic Ca2+, ends muscle contraction and allows muscle relaxation.

cal·ci·um pump

(kal'sē-ŭm pŭmp)
A membranal protein that can transport calcium ions across the membrane using energy from ATP.
References in periodicals archive ?
'We purified the part of the calcium pump that interacts with calcium-activated calmodulin, and we managed to crystallise a protein complex.
The fact that two calmodulin proteins are involved in the regulation of the calcium pump activity means that the calcium pump has three steps.
The researchers also used mathematical network modelling to further identify whether the calcium pump works differently depending on whether it is activated by zero, one or two calmodulin proteins.
Travel Business Review-October 23, 2012--UNIVERSITY OF COPENHAGEN - Danish researchers release ground-breaking knowledge about calcium pumps in cells(C)2012] ENPublishing - http://www.enpublishing.co.uk
Researchers from the Danish National Research Foundation's PUMPkin Centre at both the University of Copenhagen and Aarhus University have now shown that calcium pumps in the cell's outer membrane adjust the pump speed very accurately to the calcium concentration.
Previous studies have shown that calcium pumps in both animals and plants work together with a protein called calmodulin.
In the aging heart, free radicals damage proteins, membranes, and calcium pumps on the sarcoplasmic reticulum that myocytes need to produce contractions.
Structural changes in the calcium pump accompanying the dissociation of calcium.
Sacroplasmic reticulum calcium pump in cardiac and slow twitch skeletal muscle but not fast twitch skeletal muscle undergoes phosphorylation by endogenous and exogenous [Ca.sup.2+]/calmodulin-dependent protein kinase.
Sarco(endo)plasmic reticulum calcium pumps: recent advances in our understanding of structure/function and biology.
(21), (23) Damage to DNA, the internal lipid membrane, and to proteins occurs, reducing the efficiency of energy production and the availability of chemical energy to energize the calcium pumps of the ce11.
Collectively, the multiple defects in calcium homeostasis from the increased release of calcium from the ER, reduction in calcium extrusion through the cell membrane, the reduction in buffering capacity, and the impairment of calcium pumps, also the impairment of the mitochondrial sinks, result in changes to neuron function and cell viability.

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