calcium current

A term for the flow of Ca2+ through specific channels, which is critical for the release of neurotransmitters from presynaptic vesicles. Voltage-gated calcium channels are divided according to the type of calcium current with which they are associated.

Calcium current types
L—Long-lasting activation.
N—Neural type.
P—Purkinje activation related to the release of neurotransmitters.
R—Poorly understood; found in cerebellar granule cells.
T—Transient activatation.

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References in periodicals archive ?

(1) It is shown that there is the basal calcium current through CatSper, which is blocked by NNC55-0396 (NNC).

Inhibition of CatSper and Hv1 Channels and NOX5 Enzyme Affect Progesterone-Induced Increase of Intracellular Calcium Concentration and ROS Generation in Human Sperm

Figure 4(a) shows the calcium current at V = 0 mV, for different numbers of non-inactivating CaVs, while Figure 4(b) shows the corresponding cases with inactivating CaVs.

Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by [Ca.sup.2+] Channels

This not only resembled in vivo tissue in terms of the parallel arrangement of cells but also showed presence of antigrade calcium current as seen in the functional heart tissue.

Engineered Biomaterial Surfaces for Neonatal Murine Cardiomyocyte Culture Toward Understanding Cardiac Hypertrophy

The depolarization to burst phase is caused by low calcium current which can be generated in our model by setting I with a low value.

Hyperbolic Modeling of Subthalamic Nucleus Cells to Investigate the Effect of Dopamine Depletion

Penner, "Depletion of intracellular calcium stores activates a calcium current in mast cells," Nature, vol.

Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells

In addition, voltage clamp measurements were performed to show that phenylpropanoid glycosides significantly inhibited the L-type calcium current, reduced the repolarizing current [I.sub.Kr], and prolonged the AP duration [37].

The Role of Biologically Active Ingredients from Natural Drug Treatments for Arrhythmias in Different Mechanisms

In ventricular myocytes, the L-type calcium current regulates excitation contraction coupling and influences the plateau height of the action potential, as well as total action potential duration [15].

L-type calcium channels do not play a critical role in chest blow induced ventricular fibrillation: commotio cordis

(1996) Presynaptic calcium current modulation by a metabotropic glutamate receptor.

Strength and precision of neurotransmission at mammalian presynaptic terminals

Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes.

Effects of eugenol on resting tension of rat atria

ER agonists can also decrease L-type calcium current (mechanism 5; Jiang et al.

Bisphenol A exposure and cardiac electrical conduction in excised rat hearts

Nelson et al., "Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons," Journal of Neuroscience, vol.

Nociceptive neurons differentially express fast and slow t-type [Ca.sup.2+] currents in different types of diabetic neuropathy

Li, "Epidermal growth factor reduces L-type voltage-activated calcium current density in GH4C1, rat pituitary cells," Neuroendocrinology, vol.

Upregulation of voltage-gated calcium channel [Ca.sup.V] 1.3 in bovine somatotropes treated with Ghrelin