calcium current

A term for the flow of Ca2+ through specific channels, which is critical for the release of neurotransmitters from presynaptic vesicles. Voltage-gated calcium channels are divided according to the type of calcium current with which they are associated.

Calcium current types
L—Long-lasting activation.
N—Neural type.
P—Purkinje activation related to the release of neurotransmitters.
R—Poorly understood; found in cerebellar granule cells.
T—Transient activatation.

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References in periodicals archive ?

The addition of 500 nM of progesterone to the bath solution of sperm can considerably increase the amplitude of the CatSper channel's calcium current.

Inhibition of the CatSper Channel and NOX5 Enzyme Activity Affects the Functions of the Progesterone-Stimulated Human Sperm

In ventricular myocytes, the L-type calcium current regulates excitation contraction coupling and influences the plateau height of the action potential, as well as total action potential duration [15].

L-type calcium channels do not play a critical role in chest blow induced ventricular fibrillation: commotio cordis

1996) Presynaptic calcium current modulation by a metabotropic glutamate receptor.

Strength and precision of neurotransmission at mammalian presynaptic terminals

The inhibitory effect of magnolol on the calcium current was expressed as percentage reduction in the steady-state current amplitude with magnolol using the equation: % inhibition = ([I.

Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type [Ca.sup.2+] channels of colonic smooth muscle cells in rats

Less commonly, amiodarone, by its non-competitive beta antagonism and blockade of inward L type calcium current, may actually reduce EADs and prevent TdP.

Treatment of methadone-induced torsades de pointes with lidocaine

VASSORT (1992): <<Properties of the low-threshold calcium current in bullfrog atrial cells.

Dissociation enzyme effects on the biophysical properties of calcium current in acutely isolated rat ventricular myocytes/Efectos de la disociacion enzimatica sobre las propiedades biofisicas de la corriente de calcio en miocitos ventriculares de rata

Using a careful analysis of correlations between the course of alcohol withdrawal seizures and the expression of calcium currents, Georgetown University Medical Center researchers found that the enhancement of total calcium current density in pre-clinical animal studies occur prior to the onset of alcohol withdrawal seizures.

Why seizures occur with alcohol withdrawal

Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells.

Modulacion local de un canal operado por deposito

T type calcium current properties are not modified by calcium channel Beta subunit depletion in nodosus ganglion neurons.

Transmision sinaptica-canales de calcio y liberacion de neurotransmisores

Effects of intracellular free magnesium on calcium current in isolated cardiac myocytes.

Pharmacologic manipulation of the labyrinth with novel and traditional agents delivered to the inner ear. (Original Article)

Depletion of intracellular calcium stores activates a calcium current in mast cells.

Synta and Roche Form Discovery, Development, and Commercialization Alliance in Inflammation

Reduced calcium current density in single myocytes isolated from hypertrophied failing guinea pig hearts.

Berberine alleviates ischemic arrhythmias via recovering depressed [I.sub.to] and [I.sub.ca] currents in diabetic rats