PDE1A

(redirected from calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase)

PDE1A

A gene on chromosome 2q32.1 that encodes a cyclic nucleotide phosphodiesterase, which plays a critical role in signal transduction, regulating intracellular cyclic nucleotide concentrations by hydrolysing cAMP and/or cGMP to AMP and GMP. As with other PDE1s, PDE1A is activated by calmodulin in the presence of Ca2+.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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