calcitonin gene-related peptide receptor


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calcitonin gene-related peptide receptor

The receptor for a peptide found in trigeminal nerve sensory neurons which is a powerful dilator of cerebral and dural arteries. An infusion of the calcitonin gene-related peptide will induce MIGRAINE and the specific antagonist BIBN 4096 BS is effective in treating an attack of migraine.
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Biohaven Pharmaceutical announced that positive results from a Phase 3 pivotal clinical trial of rimegepant, Biohaven's small molecule calcitonin gene-related peptide receptor antagonist, for the acute treatment of migraine, are published in the July 12, 2019 issue of the New England Journal of Medicine.
Biohaven Pharmaceutical announced additional safety and preliminary efficacy results from its ongoing long-term, open-label safety study of its oral calcitonin gene-related peptide receptor antagonist, rimegepant.
It works by blocking a receptor called the calcitonin gene-related peptide receptor which plays a critical role in mediating the incapacitating pain of migraine.
Biohaven Pharmaceutical is presenting expanded data from two randomized, pivotal Phase 3 clinical trials of rimegepant, Biohaven's small molecule calcitonin gene-related peptide receptor antagonist, on June 30 at the American Headache Society Annual Scientific Meeting.
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